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由来生物
human
品質水準
リコンビナント
expressed in E. coli
アッセイ
≥97% (SDS-PAGE)
形状
lyophilized powder
有効性
<1 ng/mL Biological Activity EC50
分子量
16.0 kDa
包装
pkg of 4X25 μg
pkg of 25 μg
保管条件
avoid repeated freeze/thaw cycles
色
white to faint yellow cast
溶解性
water: soluble 0.025 mg, clear, colorless to faintly yellow
UniProtアクセッション番号
保管温度
−20°C
遺伝子情報
human ... FGF2(2247)
関連するカテゴリー
詳細
bFGFは、多様な臓器で発見され、幅広い細胞型で作用し、多機能的作用を有するため、ヘパリン結合増殖因子(クラスIIまたはβ)、眼由来増殖因子I、軟骨由来増殖因子、アストログリア増殖因子II5など、多数の同義語が認められます。精製ウシおよびヒトbFGF は、3個の連続したアミノ酸が異なっており3、生物学的および免疫学的に交差反応します。
引用
1. Gospodarowicz, D., Localization of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth. Nature, 249, 123-127 (1974).
2. Gospodarowicz, D. et al., Structural characterization and biological functions of fibroblast growth factor. Endo. Rev., 8, 95-114 (1987).
3. Esch, F. et al., Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA, 82, 6507-6511 (1985).
4. Neufeld, G., and Gospodarowicz, D., Basic and acidic fibroblast growth factors interact with the same cell surface receptors. J. Biol. Chem., 261, 5631-5637 (1986).
5. Lobb, R.R. et al., Purification of heparin-binding growth factors. Anal. Biochem., 154, 1-14 (1986).
6. Abraham, J.A., Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J., 5, 2523- 2528 (1986).
2. Gospodarowicz, D. et al., Structural characterization and biological functions of fibroblast growth factor. Endo. Rev., 8, 95-114 (1987).
3. Esch, F. et al., Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA, 82, 6507-6511 (1985).
4. Neufeld, G., and Gospodarowicz, D., Basic and acidic fibroblast growth factors interact with the same cell surface receptors. J. Biol. Chem., 261, 5631-5637 (1986).
5. Lobb, R.R. et al., Purification of heparin-binding growth factors. Anal. Biochem., 154, 1-14 (1986).
6. Abraham, J.A., Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J., 5, 2523- 2528 (1986).
保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
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