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主要文書

EHU133481

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human TMEM173

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About This Item

UNSPSCコード:

41105324

NACRES:

NA.51

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SIRNA

MISSION^® siRNA Product Offerings

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SHCLNG

MISSION^® shRNA

SHRNA

MISSION^® shRNA Product Offerings

HS20622B

Dropper Bulb

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SHCLND

MISSION^® shRNA

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SAB4502446

Anti-CXCR7 antibody produced in rabbit

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SML3910

Yoda2

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SIC001

MISSION^® siRNA Universal Negative Control #1

OLIGO

カスタムDNAオリゴ（Custom DNA Oligos）

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EMU056071

MISSION^® esiRNA

詳細

品質水準

100

製品種目

MISSION^®

フォーム

lyophilized powder

esiRNA cDNA標的配列

GATATCTGCGGCTGATCCTGCCAGAGCTCCAGGCCCGGATTCGAACTTACAATCAGCATTACAACAACCTGCTACGGGGTGCAGTGAGCCAGCGGCTGTATATTCTCCTCCCATTGGACTGTGGGGTGCCTGATAACCTGAGTATGGCTGACCCCAACATTCGCTTCCTGGATAAACTGCCCCAGCAGACCGGTGACCATGCTGGCATCAAGGATCGGGTTTACAGCAACAGCATCTATGAGCTTCTGGAGAACGGGCAGCGGGCGGGCACCTGTGTCCTGGAGTACGCCACCCCCTTGCAGACTTTGTTTGCCATGTCACAATACAGTCAAGCTGGCTTTAGCCGGGAGGATAGGCTTGAGCAGGCCAAACTCTTCTGCCGGACACTTGAGGACATCCTGGCAGATGCCCCTGAGTCTCAGAACAACTGCCGCCTCATTGCCTACCAGGAACC

Ensembl |ヒトアクセッション番号

ENSG00000184584

NCBIアクセッション番号

NM_198282

輸送温度

ambient

保管温度

−20°C

遺伝子情報

human ... TMEM173(340061) , TMEM173(340061)

詳細

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法的情報

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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STING Is Involved in Antiviral Immune Response against VZV Infection via the Induction of Type I and III IFN Pathways.

Ji-Ae Kim et al.

The Journal of investigative dermatology, 137(10), 2101-2109 (2017-06-26)

Varicella zoster virus (VZV) is a human-restricted α-herpesvirus that exhibits tropism for the skin. The VZV host receptors and downstream signaling pathways responsible for the antiviral innate immune response in the skin are not completely understood. Here, we show that

Molecular Characterization, Expression and Functional Analysis of Chicken STING.

Jin-Shan Ran et al.

International journal of molecular sciences, 19(12) (2018-11-25)

Innate immunity is an essential line of defense against pathogen invasion which is gained at birth, and the mechanism involved is mainly to identify pathogen-associated molecular patterns through pattern recognition receptors. STING (stimulator of interferon genes) is a signal junction

rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections.

So-Young Lee et al.

Frontiers in immunology, 10, 1735-1735 (2019-08-14)

Hepatitis B virus infection is a serious global health problem and causes life-threatening liver disease. In particular, genotype C shows high prevalence and severe liver disease compared with other genotypes. However, the underlying mechanisms regarding virological traits still remain unclear.

Low-dose carboplatin reprograms tumor immune microenvironment through STING signaling pathway and synergizes with PD-1 inhibitors in lung cancer.

Li Zhou et al.

Cancer letters, 500, 163-171 (2020-12-06)

Although the combination of chemotherapy and immunotherapy is a hot topic in lung cancer, little is understood regarding the possible mechanisms behind their synergy. Moreover, safety is a major concern for clinicians while performing chemotherapy. Therefore, it is important to

Functional characterization and subcellular localization of miiuy croaker cytosolic MITA involved in activation NF-κB pathway.

Junxia Cui et al.

Fish & shellfish immunology, 68, 29-36 (2017-07-08)

In the innate immune responses in host protection, pattern recognition receptors are involve in a variety of sensing mechanisms to recognize and counter pathogen invasion. Recently, a resident endoplasmic reticulum adaptor, stimulator of interferon genes (STING) protein, also called MPYS

主要文書

MISSION^® esiRNA