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由来生物
microbial
品質水準
形状
powder
溶解性
water: 20 mg/mL, clear, faintly yellow to yellow
保管温度
−20°C
SMILES記法
[H]C(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)N[C@@H](CC(C)C)C(O)=O)[C@]1([H])CCNC(=N)N1
InChI
1S/C21H36N8O7/c1-10(2)8-14(19(34)35)28-21(36)29-16(12-6-7-24-20(23)27-12)18(33)26-13(4-5-15(22)31)17(32)25-11(3)9-30/h9-14,16H,4-8H2,1-3H3,(H2,22,31)(H,25,32)(H,26,33)(H,34,35)(H3,23,24,27)(H2,28,29,36)/t11-,12-,13-,14-,16-/m0/s1
InChI Key
IJWCGVPEDDQUDE-YGJAXBLXSA-N
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生物化学的／生理学的作用
強力な、不可逆性エラスターゼ阻害剤。エラスタチナールは、白血球由来のエラスターゼよりも膵臓由来のエラスターゼに対してはるかに強力な阻害効果を示します。
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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Sandra Cerqueira Barros et al.
Enzyme and microbial technology, 50(2), 107-114 (2012-01-10)
Elastase plays an important role in wound healing process, degrading damaged tissue and allowing complete tissue recovery. The levels of human neutrophil elastase (HNE) are usually controlled by endogenous inhibitors. However, in the presence of high levels of elastase, like
De-Peng Jiang et al.
Journal of Korean medical science, 26(6), 778-784 (2011-06-10)
Scutellarin is a flavonoid extracted from a traditional Chinese herb, Erigeron breviscapus. The present study investigated the effect of scutellarin on MUC5AC mucin production and the possible mechanism. Human bronchial epithelial 16 (HBE16) cells were pretreated with scutellarin for 60
T Yagi et al.
Cancer letters, 10(4), 301-307 (1980-10-01)
Effects of elastatinal, a protease inhibitor, on DNA repair and its cytotoxicity were investigated in normal human, xeroderma pigmentosum and Chinese hamster V79 cells. There were no effects of elastatinal on DNA repair and UV-induced sister chromatid exchanges, and all
P Paul et al.
Carcinogenesis, 2(4), 255-259 (1981-01-01)
Microbial protease inhibitors elastatinal and leupeptin were tested for cytotoxicity and for effects on spontaneous and u.v.-induced 6-thioguanine-resistant (6TGr) mutation and sister-chromatid exchange (SCE) in V79 Chinese hamster cells. Continuous treatment with elastatinal exhibited marked cytotoxicity, while leupeptin was almost
Valentina Grano et al.
Biotechnology progress, 20(3), 968-974 (2004-06-05)
The inhibitory power of three different active Nylon membranes, separately loaded with three different protease inhibitors, was studied with the aim of reducing the increased elastase concentration occurring during hemodialysis or extracorporeal blood circulation in patients undergoing cardiopulmonary bypass. Chemical
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