CN406-05

Canine Osteoblasts: CnOb (Cryovial)

• UNSPSCコード: 41106514
• NACRES: NA.81

特性

• 由来生物: canine bone (normal)
• 包装: pkg of 500,000 cells
• メーカー／製品名: Cell Applications, Inc
• 成長モード: Adherent
• 核型: 2n = 78
• 形態: osteoblast
• テクニック: cell culture | mammalian: suitable
• 関連疾患: arthritis; osteoporosis
• 輸送温度: dry ice
• 保管温度: −196°C

詳細

詳細

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Canine osteoblasts provide an excellent model system for studies relevant to the skeletal system, including mechanisms of cancerogenesis.

Canine osteoblasts have been used to define a biomarker profile of canine osteosarcoma (Milovancev, 2013), elucidate the roles of oncogenic STAT3 (Fossey, 2009, 2011) and canonical Wnt signaling (Piskun, 2013) pathways, and to develop personalized osteosarcoma treatments by testing Src inhibitor dasatinib (Davis, 2013), procaspase-3 activating compound PAC-1 (Book, 2012), HSP90 inhibitor STA-1474 (McCleese, 2009) and STAT3 inhibitor LLL12 (Couto, 2012, 2013).

Characterization: Positive for bone mineralization.

細胞株の由来

Bone

アプリケーション

model for skeletal system research, signaling pathways, bone morphogenesis, gene expression, cell activation and proliferation, wound healing, bone formation and regeneration, treatment strategies, tissue engineering, in vitro bone models, mineralization, hormone treatments

構成

Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO

調製ノート

• 1st passage, >500,000 cells in Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 10 doublings

継代と培養方法

Please refer to the CnOb Culture Protocol.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable