C4915

S-(+)-クロルフェニラミン マレイン酸塩

• 別名: (S)-γ-(4-クロロフェニル)-N,N-ジメチル-2-ピリジンプロパンアミン マレイン酸塩
• 実験式（ヒル表記法）: C₁₆H₁₉ClN₂ · C₄H₄O₄
• CAS番号: 2438-32-6
• 分子量: 390.86
• EC Number: 219-450-6
• MDL番号: MFCD00079046
• UNSPSCコード: 12352116
• PubChem Substance ID: 24278317
• NACRES: NA.77

特性

• 形状: powder
• 品質水準: 200
• オーガナイザー: Bayer
• SMILES記法: [H]\C(=C(/[H])C(O)=O)C(O)=O.CN(C)CC[C@@H](c1ccc(Cl)cc1)c2ccccn2
• InChI: 1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1
• InChI Key: DBAKFASWICGISY-DASCVMRKSA-N
• 遺伝子情報: human ... HRH1(3269)

詳細

詳細

Chlorpheniramine maleate is a cationic amphiphilic anti-histamine agent, which is composed of a hydrophobic ring structure and a hydrophilic side chain with a charged cationic amino group.

アプリケーション

S-(+)-Chlorpheniramine maleate salt has been used to study the anticholinergic effect of Achillea millefolium and Portulaca olerace on muscarinic receptors of guinea pig tracheal smooth muscle.

生物化学的／生理学的作用

H₁ヒスタミンレセプタ-アンタゴニストです。 活性異性体です。

特徴および利点

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301
• 注意書き: P264 - P270 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges