C111040

DMT-dC(bz) ホスホロアミダイト

configured for MerMade

• 別名: DMT-dC(bz)アミダイト, N-ベンゾイル-5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-デオキシシチジン,3'-[2-シアノエチルN,N-?ビス(1-メチルエチル)ホスホロアミダイト], N4-ベンゾイル-5'-O-(4,4'-ジメトキシトリチル)-2'-デオキシシチジン-3'-O-[O-(2-シアノエチル)-N,N'-ジイソプロピルホスホロアミダイト], シチジン、N-ベンゾイル-5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-デオキシ-,3'-[2-シアノエチルビス(1-メチルエチル)ホスホロアミダイト]
• 実験式（ヒル表記法）: C₄₆H₅₂N₅O₈P
• CAS番号: 102212-98-6
• 分子量: 833.91
• MDL番号: MFCD00036315
• UNSPSCコード: 41116107
• PubChem Substance ID: 329774850
• NACRES: NA.51

特性

• 由来生物: non-animal source (no BSE/TSE risk)
• 品質水準: 200
• タイプ: for DNA synthesis
• 製品種目: Proligo Reagents
• アッセイ: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• 形状: powder or granules
• テクニック: oligo synthesis: suitable
• 不純物: ≤0.3 wt. % water content (Karl Fischer)
• 色: white to off-white
• λ: conforms (UV/VIS Identity)
• 適合性: configured for MerMade
• 核酸プロファイル: base: deoxycytidine; base protecting group: benzoyl; 2' protecting group: none; 5' protecting group: DMT; deprotection: standard
• 保管温度: 2-8°C
• SMILES記法: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(=O)c4ccccc4)=NC3=O)(c5ccccc5)c6ccc(OC)cc6
• InChI: 1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1
• InChI Key: PGTNFMKLGRFZDX-SALLYJDFSA-N

詳細

詳細

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites :

• Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
• The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides

The product belongs to MerMade synthesizers.

包装

C111040-1G packaged in a 1 oz bottle with a 28-400 cap
C111040-10G packaged in a 8 oz bottle with a 28-400 cap
C111040-6x5G packaged in a 8 oz bottle with a 28-400 cap
C111040-6x10G packaged in a 8 oz bottle with a 28-400 cap
C111040-20x10G packaged in a 1 L bottle with GL 45

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable