B0936

BRL 50481

≥98% (HPLC), solid

• 別名: 5-Nitro-2,N,N-trimethylbenzenesulfonamide
• 実験式（ヒル表記法）: C₉H₁₂N₂O₄S
• CAS番号: 433695-36-4
• 分子量: 244.27
• MDL番号: MFCD03039912
• UNSPSCコード: 12352200
• PubChem Substance ID: 24277757
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: solid
• 色: white to off-white
• 溶解性: DMSO: >10 mg/mL; H₂O: insoluble
• オーガナイザー: GlaxoSmithKline
• 保管温度: 2-8°C
• SMILES記法: CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
• InChI: 1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3
• InChI Key: IFIUFCJFLGCQPH-UHFFFAOYSA-N
• 遺伝子情報: human ... PDE7A(5150) , PDE7B(27115)

詳細

生物化学的／生理学的作用

BRL 50481 is a potent and selective PDE7 inhibitor (IC50 = 260 nM).

特徴および利点

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法的情報

Sold for research purposes under agreement from GlaxoSmithKline

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)