おすすめの製品
由来生物
mouse
結合体
alkaline phosphatase conjugate
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
MY-32, monoclonal
フォーム
buffered aqueous glycerol solution
交差性
rat, chicken, rabbit, mouse, human, bovine, guinea pig, feline
テクニック
direct immunofluorescence: 1:150 using formalin-fixed, paraffin-embedded human or animal skeletal muscle sections
アイソタイプ
IgG1
UniProtアクセッション番号
輸送温度
wet ice
保管温度
2-8°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... MYH1(4619) , MYH2(4620)
mouse ... Myh1(17879) , Myh2(17882)
rat ... Myh1(287408) , Myh2(691644)
類似した製品をお探しですか？ 訪問 製品比較ガイド
詳細
エピトープをミオシン重鎖に局在させます。骨格筋で見られるファスト（II型）イソミオシンおよび新生児イソミオシン分子を染色しますが、心筋、平滑筋または培養細胞中の非筋肉ミオシンは染色しません。ヒト横紋筋肉腫と反応しません。
Monoclonal Anti-Myosin (Skeletal, Fast) (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
特異性
Monoclonal Anti-Myosin (Skeletal, Fast) specifically binds to an epitope in adult rat skeletal myosin heavy chains IIa, IIb and IId (IIx) (in fast-twitch fibers)†. The antibody product is also reactive in humans, bovines, cats, rabbits, mice, guinea pigs and chickens.
免疫原
ウサギ筋肉のミオシン。
アプリケーション
過去に負傷したスポーツマンから採取した血清サンプル中のミオシン（ファスト）濃度が、モノクローナルマウス抗ミオシン（骨格筋/ファスト）を一次抗体として1:90000に希釈して使用したウェスタンブロットで測定されました。
Monoclonal Anti-Myosin (Skeletal, Fast) Alkaline Phosphatase antibody produced in mouse has been used for the detection and localization of skeletal muscle fast and neonatal myosins using immunohistochemistry. It may be used in muscle fiber typing, in studies of in vivo and in vitro muscle development and in the diagnosis of rhabdomyosarcomas.
生物化学的／生理学的作用
Myosin (Skeletal, Fast) is useful not only in fiber typing but also in detection of myogenic tumors. It enables retrospective as well as prospective fiber typing using formalin-fixed, paraffin-embedded material.
Myosins are motor proteins that interact with actin filaments to regulate cell movement. Myosins also modulate cell shape and signaling. Skeletal muscle myosins have three ′fast′ myosin heavy chains isoforms (IIa, IIx, and IIb), a ′slow′ beta-myosin heavy chain isoform and three major myosin light-chain (MLC) isoforms. These myosin isoforms regulate skeletal muscle shortening.
物理的形状
0.05M Trisバッファ-溶液 (pH 8.0, 1%BSA, 1mM MgCl2, 50%グリセロ-ル, 15mMアジ化ナトリウム含有)。
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
適切な製品が見つかりませんか。
製品選択ツール.をお試しください
保管分類コード
10 - Combustible liquids
WGK
WGK 2
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
A4335-VAR:
A4335-BULK:
A4335-.2ML:
この製品を見ている人はこちらもチェック
F Russell Westwood et al.
Toxicologic pathology, 36(2), 345-352 (2008-03-26)
Rosuvastatin is a relatively new member of the statin family (HMG-CoA reductase inhibitors), with superior lipid-lowering effects and a pattern of clinical side effects, including a low incidence of myopathy, similar to other widely prescribed statins. This article describes investigations
Christopher Taber et al.
Sports (Basel, Switzerland), 6(2) (2018-06-19)
The purpose of this study was to examine the effects of a recovery supplement compared with a placebo on muscle morphology in trained weightlifters. Vastus lateralis and muscle fiber cross sectional area of type I and type II fibers were
Katy C Liu et al.
Bioarchitecture, 2(5), 158-170 (2012-09-08)
The development of cell-cell junctions was a fundamental step in metazoan evolution, and human health depends on the formation and function of cell junctions. Although it has long been known that actin and conventional myosin have important roles in cell
A J Harris et al.
Development (Cambridge, England), 107(4), 751-769 (1989-12-01)
The expression of myosin isoforms was studied during development of calf muscles in foetal and neonatal rats, using monoclonal antibodies against slow, embryonic and neonatal isoforms of myosin heavy chain (MHC). Primary myotubes had appeared in all prospective rat calf
Vivi F H Jensen et al.
Basic & clinical pharmacology & toxicology, 122(1), 165-175 (2017-08-18)
Peripheral neuropathy is one of the most common complications of diabetic hyperglycaemia. Insulin-induced hypoglycaemia (IIH) might potentially exacerbate or contribute to neuropathy as hypoglycaemia also causes peripheral neuropathy. In rats, IIH induces neuropathy associated with skeletal muscle changes. Aims of
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）