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詳細
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.
特異性
Anti-human IgG recognizes human IgG (whole molecules). Goat anti-human is purified by ion exchange chromatography and then covalently bound to agarose.
免疫原
Pooled normal human serum
アプリケーション
Anti-human IgG (whole molecule) is suitable for immunoelectrophoresis. Antibody depletion from normal human serum was carried out by treating diluted serum with 50 microl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 °.
Antibody depletion from normal human serum was carried out by treating diluted serum with 50 μl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 degrees.
生物化学的／生理学的作用
IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.
物理的形状
0.01 M PBS(pH 7.4, 15 mMアジ化ナトリウム含有)の懸濁液
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
T A Brighton et al.
The Biochemical journal, 340 ( Pt 1), 59-67 (1999-05-07)
Considerable interest is currently focused on the interactions of beta-2 glycoprotein I (beta2GPI) and anti-phospholipid antibodies with anionic phospholipids in an attempt to understand the association between these antibodies and clinical diseases such as thrombosis. The interactions of beta2GPI and
J Raper et al.
Infection and immunity, 67(4), 1910-1916 (1999-03-20)
Natural resistance of humans to the cattle pathogen Trypanosoma brucei brucei has been attributed to the presence in human serum of nonimmune factors that lyse the parasite. Normal human serum contains two trypanosome lytic factors (TLFs). TLF1 is a 500-kDa
A revised nomenclature for allergy: an EAACI position statement from the EAACI nomenclature task force
Johansson SGO, et al.
Allergy, 56(9), 813-824 (2001)
Placental transfer of IgG subclasses in a Japanese population.
Hashira S, et al.
Pediatrics International, 42(4) (2000)
Structure and function of immunoglobulins.
Schroeder Jr H W and Cavacini L
The Journal of Allergy and Clinical Immunology, 125(2), S41-S52 (2010)
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