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Key Documents

905H-0

Sigma-Aldrich

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002)

Mouse and Rabbit Monoclonal Antibody

別名:

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002) Mouse and Rabbit Monoclonal Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

mouse
rabbit

品質水準

100
500

結合体

unconjugated

抗体製品の状態

purified immunoglobulin

抗体製品タイプ

primary antibodies

クローン

EP1601Y + LL002, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

形状

buffered aqueous solution

化学種の反応性

human

包装

bottle of 1.0 mL predilute (905H-07)
bottle of 7.0 mL predilute (905H-08)

メーカー/製品名

Cell Marque

濃度

0.1-1.5 μg/mL (predilute)

アイソタイプ

IgG3
IgG

輸送温度

wet ice

保管温度

2-8°C

遺伝子情報

human ... KRT5(3852)

詳細

Cytokeratin 5 is an intermediate filament protein of 58 kD molecular wt. amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-Cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas immunostain with CK5. Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors. Anti-CK5, along with anti-CK14, has found application in identifying the basaloid phenotype of breast carcinoma, a tumor with poor prognosis.

品質


IVD

IVD

IVD

RUO

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

調製ノート

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その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 728-729 (2014)
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 212-212 (2014)
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 212-212 (2014)
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 728-729 (2014)
David J Dabbs et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19(11), 1506-1511 (2006-08-31)
The basal phenotype of breast carcinoma was demonstrated from a study of gene expression profiles, which demonstrated five carcinoma phenotypes with differing immunohistologic profiles and outcomes. The basal phenotype, so-named because of an immunohistologic profile that is similar to myoepithelial

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