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由来生物
rabbit
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
EP121, monoclonal
詳細
For In Vitro Diagnostic Use in Select Regions (See Chart)
形状
buffered aqueous solution
化学種の反応性
human
包装
vial of 0.1 mL concentrate (395R-14)
vial of 0.5 mL concentrate (395R-15)
bottle of 1.0 mL predilute (395R-17)
vial of 1.0 mL concentrate (395R-16)
bottle of 7.0 mL predilute (395R-18)
メーカー／製品名
Cell Marque™
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
アイソタイプ
IgG
コントロール
Burkitt lymphoma, prostate carcinoma
輸送温度
wet ice
保管温度
2-8°C
視覚化
nuclear
遺伝子情報
human ... MYC(4609)
詳細
c-Myc is a transcription factor that drives the growth and proliferation of cells. c-Myc isamplified in many different solid and hematopoietic tumors. Immunohistochemistry forc-Myc protein is used to identify the presence of a c-Myc translocation in various tumors,most frequently to aid in the diagnosis of Burkitt lymphoma.
品質
 IVD |  IVD |  IVD |  RUO |
関連事項
c-Myc Positive Control Slides, Product No. 395S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法的情報
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Christopher W Toon et al.
PloS one, 9(2), e87456-e87456 (2014-02-08)
MYC over-expression as determined by molecular means has been reported as a favorable prognostic biomarker in colorectal carcinoma (CRC). However MYC expression analysis is not available in the routine clinical setting. We investigated whether immunohistochemistry (IHC) for the myc protein
Bora Gurel et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21(9), 1156-1167 (2008-06-24)
The MYC onco-protein is a transcription factor that regulates cell proliferation, metabolism, protein synthesis, mitochondrial function and stem cell renewal. A region on chromosome 8q24 encompassing the MYC locus is amplified in prostate cancer, but this occurs mostly in advanced
Tina Marie Green et al.
The American journal of surgical pathology, 36(4), 612-619 (2012-02-09)
Determining the presence of MYC gene rearrangements is becoming an increasingly important part of the diagnostic workup in aggressive lymphoma. Cytogenetic MYC alterations aid in differentiating diffuse large B-cell lymphoma (DLBCL) from Burkitt lymphoma. In addition, MYC aberrations are associated
Sietse M Aukema et al.
Blood, 117(8), 2319-2331 (2010-12-02)
In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double- hit (DH) lymphomas that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another
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