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Merck
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主要文書

安全性情報

330M-1

Sigma-Aldrich

S-100 (4C4.9) Mouse Monoclonal Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

mouse

品質水準

100
500

結合体

unconjugated

抗体製品の状態

diluted ascites fluid

抗体製品タイプ

primary antibodies

クローン

4C4.9, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

フォーム

buffered aqueous solution

化学種の反応性

human

包装

vial of 0.1 mL concentrate (330M-14)
vial of 0.5 mL concentrate (330M-15)
bottle of 1.0 mL predilute (330M-17)
vial of 1.0 mL concentrate (330M-16)
bottle of 7.0 mL predilute (330M-18)

メーカー／製品名

Cell Marque™

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

アイソタイプ

IgG2a

コントロール

melanoma

輸送温度

wet ice

保管温度

2-8°C

視覚化

cytoplasmic, nuclear

遺伝子情報

human ... S100A1(6271)

詳細

S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells.Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Despite the fact that S-100 protein is an ubiquitous substance, its demonstration is of great value in the identification of several neoplasms, particularly melanomas.

品質


IVD
IVD
IVD
RUO

関連事項

S-100 Positive Control Slides, Product No. 330S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

330M-14-RUO:
330M-15:
330M-18:
330M-16-RUO:
330M-16:
330M-17-RUO:
330M-18-RUO:
330M-14:
330M-13:
330M-17:
330M-15-RUO:
330M-10:
330M-12:
330M-11:
330M-10-RUO:

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
0000299350
0000299351
0000299351
0000299350
1425201A-Z

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特定のバージョンが必要な場合は、ロット番号またはバッチ番号で特定の証明書を検索できます。

COAを検索

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

T Nakajima et al.
The American journal of surgical pathology, 6(8), 715-727 (1982-12-01)
The presence of S-100 protein was immunohistochemically studied in many types of formalin-fixed and paraffin-embedded tumors (260 cases). Peripheral nerve tumors, i.e., schwannomas, neurofibromas, granular cell tumors, and neurogenic sarcomas were demonstrated to contain variable amounts of S-100 protein in
H J Kahn et al.
American journal of clinical pathology, 79(3), 341-347 (1983-03-01)
Normal tissues and various tumors were examined for S100 protein, using anti-S100 protein antiserum, in an immunoperoxidase reaction. Among normal tissues, in addition to the previously reported presence of S100 protein in some neurons, glial, and Schwann cells of the
K M McLaren et al.
Human pathology, 27(7), 633-636 (1996-07-01)
In general, the diagnosis of papillary carcinoma of the thyroid is readily achieved based on a defined aggregate of histopathologic features. A papillary architecture is an important but not pivotal component of the diagnosis. The recognition of classic nuclear features
Purvisha Patel et al.
Journal of the American Academy of Dermatology, 46(2), 264-270 (2002-01-25)
Malignant myxoid melanoma (MMM) is a rarely reported variant of malignant melanoma, which can often be confused with other mucin-containing neoplasms. A retrospective study of 3 cases of MMM and a review of the English-language literature was performed. MMM affects
L Monda et al.
Human pathology, 16(3), 287-293 (1985-03-01)
In an effort to investigate the utility of immunostaining for S-100 protein in the differential diagnosis of chondroblastoma, the expression of S-100 protein in nine chondroblastomas was compared with that in six giant cell tumors, six aneurysmal bone cysts, four
関連する文献をすべて表示

資料

Immunohistochemistry: Current Applications in Skin Cancer

Immunohistochemistry (IHC) techniques and applications have greatly improved, dermatopathology is still largely based on H&E stained slides.This paper outlines ways in which IHC antibodies can be utilized for dermatopathology.

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