おすすめの製品
由来生物
rabbit
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
EPR3097Y, monoclonal
詳細
For In Vitro Diagnostic Use in Select Regions (See Chart)
フォーム
buffered aqueous solution
化学種の反応性
human
包装
vial of 0.1 mL concentrate (199R-14)
vial of 0.5 mL concentrate (199R-15)
bottle of 1.0 mL predilute (199R-17)
vial of 1.0 mL concentrate (199R-16)
bottle of 7.0 mL predilute (199R-18)
メーカー／製品名
Cell Marque®
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
アイソタイプ
IgG
コントロール
Ewing’s sarcoma
輸送温度
wet ice
保管温度
2-8°C
視覚化
cytoplasmic, membranous
遺伝子情報
human ... CD99(4267)
詳細
CD99, as detected with a variety of antibodies, is expressed by virtually almost all Ewings sarcoma and primitive peripheral neuroectodermal tumors (ES/PNET) and demonstrates strong and diffuse membranous staining. Other tumors that may show CD99 expression include neuroendocrine carcinomas, mesenchymal chondrosarcomas, solitary fibrous tumors, synovial sarcomas, vascular tumors, small round blue cell group of pediatric neoplasms, lymphoblastic lymphoma, acute myeloid leukemia, and myeloid sarcoma. However, strong and diffuse membranous reactivity for CD99 favors ES/PNET over the other diagnostic considerations. The other CD99+ tumors usually show cytoplasmic and more heterogeneous staining. Therefore, when making a final diagnostic interpretation, CD99 must be considered in a panel with other antibodies.
品質
 IVD |  IVD |  IVD |  RUO |
関連事項
CD99 Positive Control Slides, Product No. 199S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法的情報
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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試験成績書（COA）
Lot/Batch Number
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 126-126 (2014)
Joseph D Khoury
Advances in anatomic pathology, 12(4), 212-220 (2005-08-13)
The Ewing sarcoma family of tumors (ESFT) comprises morphologically heterogeneous tumors that are characterized by nonrandom chromosomal translocations involving the EWS gene and one of several members of the ETS family of transcription factors. The translocation t(11;22)(q24;q12) is the most
Ewing's sarcoma: new approaches to histogenesis and molecular plasticity.
W J Rettig et al.
Laboratory investigation; a journal of technical methods and pathology, 66(2), 133-137 (1992-02-01)
E J Fellinger et al.
The American journal of surgical pathology, 16(8), 746-755 (1992-08-01)
The HBA71 antigen is an M(r) 30,000/32,000 cell surface glycoprotein (p30/32MIC2), encoded by the pseudoautosomal MIC2 gene on chromosomes X and Y, that is expressed in Ewing's sarcomas. Immunohistochemical studies demonstrate a striking specificity for HBA71 among neoplasms of diverse
I M Ambros et al.
Cancer, 67(7), 1886-1893 (1991-04-01)
This study reports on the specific expression of the MIC2 gene, a pseudoautosomal gene located on the short arms of the X and Y chromosomes, on Ewing's sarcoma (ES) and peripheral primitive neuroectodermal tumor (pPNET) cells. The gene product, a
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