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Key Documents

安全性情報

171R-1

Sigma-Aldrich

CD71 (EP232) Rabbit Monoclonal Primary Antibody

別名:

TFR1, TRF, TRFR, Transferrin Receptor 1, p90, transferrin receptor (p90, CD71)

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

EP232, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

形状

buffered aqueous solution

化学種の反応性

human

包装

vial of 0.1 mL concentrate (171R-14)
vial of 0.1 mL concentrate Research Use Only (171R-14-RUO)
vial of 0.5 mL concentrate (171R-15)
vial of 1.0 mL concentrate (171R-16)
vial of 1.0 mL concentrate Research Use Only (171R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (171R-17-RUO)
vial of 1.0 mL predilute ready-to-use (171R-17)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (171R-18-RUO)
vial of 7.0 mL predilute ready-to-use (171R-18)

メーカー/製品名

Cell Marque

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

アイソタイプ

IgG

コントロール

bone marrow

輸送温度

wet ice

保管温度

2-8°C

視覚化

cytoplasmic, membranous

詳細

Transferrin receptor 1 (CD71) is expressed on placental syncytiotrophoblasts, myocytes, basal keratinocytes, hepatocytes, endocrine pancreas, spermatocytes, and erythroid precursors. The level of transferrin receptor expression is highest in early erythroid precursors through the intermediate normoblast phase, after which expression decreases through the reticulocyte phase. The maturation of erythrocytes results in loss of transferrin receptor expression. AntiCD71 is useful in identifying erythroid precursors. The high level of transferrin receptor within erythroid precursors makes anti-CD71 an excellent marker for evaluation of erythroid precursors within bone marrow biopsy specimens and shows the following features: 1) distinct membranous and cytoplasmic staining pattern, which is easily recognized in bone marrow biopsy; 2) restriction to erythroid lineage within bone marrow biopsy specimens; 3) CD71 expression decreases with the maturation of erythrocytes, with the highest level seen in early forms and the lowest level in late normoblast stage, and most importantly; 4) mature erythrocytes do not express CD71.

品質

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

関連事項

CD71 Positive Control Slides, Product No. 171S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide

調製ノート

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その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

171R-17-RUO:
171R-14-RUO:
171R-16-RUO:
171R-14:
171R-11:
171R-18-RUO:
171R-16:
171R-15:
171R-12:
171R-17:
171R-18:
171R-13:
171R-15-RUO:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Changes in cell surface antigen expression during hemopoietic differentiation.
Sieff C, Bicknell D, Caine G, et al.
Blood, 60(3), 703-713 (1982)
Expression of transferrin receptor on murine hematopoietic progenitors.
Lesley J, Hyman R, Schulte R, et al.
Cellular Immunology, 83(1), 14-25 (1984)
Cell surface antigen expression in human erythroid progenitors: erythroid and megakaryocytic markers.
Nakahata T and Okumura N
Leukemia & Lymphoma, 13(5-6), 401-409 (1994)
T Nakahata et al.
Leukemia & lymphoma, 13(5-6), 401-409 (1994-05-01)
This review summarizes the changes in cell surface antigen expression during proliferation and differentiation of human erythroid progenitors. The content is based on our experimental data obtained from complement-mediated cytotoxicity assays against hematopoietic progenitors and a combined technique of sequential
P Ponka et al.
The international journal of biochemistry & cell biology, 31(10), 1111-1137 (1999-12-03)
The transferrin receptor is a membrane glycoprotein whose only clearly defined function is to mediate cellular uptake of iron from a plasma glycoprotein, transferrin. Iron uptake from transferrin involves the binding of transferrin to the transferrin receptor, internalization of transferrin

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