おすすめの製品
由来生物
mouse
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
2B11 & PD7/26, monoclonal
詳細
For In Vitro Diagnostic Use in Select Regions (See Chart)
フォーム
buffered aqueous solution
交差性
human
包装
vial of 0.1 mL concentrate (145M-94)
vial of 0.5 mL concentrate (145M-95)
bottle of 1.0 mL predilute (145M-97)
vial of 1.0 mL concentrate (145M-96)
bottle of 7.0 mL predilute (145M-98)
メーカー／製品名
Cell Marque®
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
アイソタイプ
IgG1κ
コントロール
tonsil
輸送温度
wet ice
保管温度
2-8°C
視覚化
membranous
遺伝子情報
human ... PTPRC(5788)
詳細
Anti-CD45 (anti-leukocyte common antigen) is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody; therefore a positive result is highly indicative of hematolymphoid origin. Certain types of hematolymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of the hematopoietic lineage and is present in most benign and malignantlymphocytes as well as plasma cell precursors.
品質
 IVD |  IVD |  IVD |  RUO |
関連事項
CD45 (LCA) Positive Control Slides, Product No. 145S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法的情報
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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試験成績書（COA）
Lot/Batch Number
P J Kurtin et al.
Human pathology, 16(4), 353-365 (1985-04-01)
Immunohistochemical localization of human leukocyte common antigen (LCA), a major membrane glycoprotein restricted to leukocytes, was evaluated in paraffin sections of a wide variety of hematopoietic and nonhematopoietic tissues (294 specimens) with monoclonal antibodies (PD7/26 and 2B11). In nonneoplastic tissues
H M Maluf et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 8(2), 155-159 (1995-02-01)
Giant cell tumor of tendon sheath (GCTTS; "nodular tenosynovitis") and fibroma of tendon sheath (FTS) have traditionally been considered to be two points in a single neoplastic continuum. However, no systematic studies have addressed this concept directly to date. To
M A Vasef et al.
American journal of clinical pathology, 108(1), 54-59 (1997-07-01)
Other studies have shown that the immunophenotype of Reed-Sternberg and Hodgkin's (RS-H) cells in Hodgkin's disease commonly changes over time, as shown by examination of multiple biopsy specimens obtained from an individual patient. In this study we analyzed 96 sequential
A Saxena et al.
American journal of clinical pathology, 112(4), 495-512 (1999-10-08)
In the multiparametric evaluation of cutaneous B-cell infiltrates (CBIs), immunoarchitectural features have been underused, and B-cell clonality alone has limited clinical usefulness. Our aim was to assess the usefulness of immunoarchitectural abnormalities (IAs) and clonality in the diagnosis of CBIs.
T Caballero et al.
Journal of clinical pathology, 48(8), 743-748 (1995-08-01)
To gain new insights into the pathogenesis and differential diagnosis of ulcerative colitis and colonic Crohn's disease. Immunohistochemistry for different leucocyte subsets was performed in biopsy specimens of the sigmoid colon and rectum from 55 patients with inflammatory bowel disease
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