108319

トリズマ®塩酸塩

EMPROVE^® EVOLVE

• 別名: トリズマ^® 塩酸塩 塩酸塩, TRIS HCl, TRIS 塩酸塩, トリス(ヒドロキシメチル)アミノメタン 塩酸塩, トロメタン塩酸塩
• 化学式: NH₂C(CH₂OH)₃ · HCl
• CAS番号: 1185-53-1
• 分子量: 157.60
• Beilstein: 3675235
• MDL番号: MFCD00012590
• UNSPSCコード: 12161700

特性

• 由来生物: synthetic
• 品質水準: 400
• 詳細: Manufactured under appropriate controls for use as a raw material in BioProcessing
• 製品種目: EMPROVE^® EVOLVE
• 形状: powder
• テクニック: cell culture | mammalian: suitable
• 不純物: Endotoxin, tested; Microbial, tested; Trace Metals, tested
• 有効pH範囲: 7.0-9.0
• pKa (25 °C): 8.1
• 適合性: suitable for manufacturing use
• その他の活性: Cytotoxicity, contains (tested); DNase, contains (tested); NICKase, contains (tested); Protease, contains (tested); RNase, contains (tested)
• SMILES記法: Cl.NC(CO)(CO)CO
• InChI: 1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
• InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N

詳細

詳細

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

アプリケーション

Tris HCl is a commonly used biological buffer. Tris/Tris HCl as a buffering system has a very broad usage in biological systems for biopharmaceutical manufacturing, cell culture, diagnostics and molecular biology. The pKa of Tris is 7.77 which corresponds closely to a physiological pH of 7.36.

Tris HCl is used as the conjugate buffer component with Tris/Tromethamine/Trizma in biopharmaceutical buffer formulations (both upstream and downstream applications), electrophoresis separations and diagnostic reagent formulations.

その他情報

すべてのバッファーのpHは、温度や濃度に依存します。トリスバッファーの場合、温度が1°C低下するとpHは約0.03上昇し、希釈10倍ごとにpHは0.03～0.05低下します。精密なアプリケーションには、適切に校正した、ガラス／カロメル複合電極のpHメーターを使用してください。

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable