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安全性情報

09111802

MS-1 cell line

09111802, human skin, mesothelioma. Loose aggregates with irregular outline, no central necrosis.

別名:

MS1 Cells

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About This Item

UNSPSCコード:
41106514

製品名

MS-1 cell line,

由来生物

human skin

フォーム

liquid

包装

tube of 5 μg 09111802-DNA-5UG
pkg of vial of cells 09111802-1VL

成長モード

Suspension

核型

Not determined

形態

Loosely packed floating aggregates with irregular outline and no central necrosis

製品

Cell line is CM2B4/MCV T, AE1/AE2, CK20, EMA, CAM5.2, chromogranin & NSE. Cell line is negative for for CK7, synaptophysin, LCA TTF-1, vimentin and CD99,

受容体

Not specified

テクニック

cell culture | mammalian: suitable

関連疾患

cancer

細胞株の由来

Human neuroendocrine skin carcinoma

細胞株の説明

MS-1 cells contain a Merkel cell polyomavirus integrated into the genome. See also MKL-1 (Sigma Catalogue number 09111801).

アプリケーション

Pathobiology of neuroendocrine skin carcinomas (NSCs) and function of cutaneous Merkel cells. The role of polyomavirus in the development of Merkel cell carcinomas (submitted for publication)

包装

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA.

DNAプロファイル

STR-PCR Data:
Amelogenin: X
CSF1PO: 10
D13S317: 11,14
D16S539: 9
D5S818: 11
D7S820: 8,9
THO1: 7,9.3
TPOX: 8
vWA: 17

培地

RPMI 1640 + 2mM Glutamine + 20% Foetal Bovine Serum (FBS).

継代と培養方法

Seed at 3 x 105 cells/ml in 5% CO2; 37°C Saturation density is approximately 106 cells/ml.

その他情報

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.
Cultures from HPA Culture Collections and supplied by Sigma are for research purposes only. Enquiries regarding the commercial use of a cell line are referred to the depositor of the cell line. Some cell lines have additional special release conditions such as the requirement for a material transfer agreement to be completed by the potential recipient prior to the supply of the cell line. Please view the Terms & Conditions of Supply for more information.
Depositor and originator: Dr Patrick Moore, University of Pittsburgh Cancer Institute, 5117 Centre Avenue Suite 1.8 Pittsburgh PA 15213

免責事項

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

保管分類コード

10 - Combustible liquids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

09111802-1VL:
09111802-VAR:
09111802-BULK:


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試験成績書(COA)

Lot/Batch Number

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文書ライブラリにアクセスする

Roland Houben et al.
Journal of virology, 84(14), 7064-7072 (2010-05-07)
Merkel cell carcinoma (MCC) is the most aggressive skin cancer. Recently, it was demonstrated that human Merkel cell polyomavirus (MCV) is clonally integrated in approximately 80% of MCC tumors. However, direct evidence for whether oncogenic viral proteins are needed for
Huichen Feng et al.
Science (New York, N.Y.), 319(5866), 1096-1100 (2008-01-19)
Merkel cell carcinoma (MCC) is a rare but aggressive human skin cancer that typically affects elderly and immunosuppressed individuals, a feature suggestive of an infectious origin. We studied MCC samples by digital transcriptome subtraction and detected a fusion transcript between

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