SMB01381

SAICAriboside

≥95% (HPLC), from synthetic, solid

• 別名: N-Succinyl-5-aminoimidazole-4-carboxamide Ribose
• 実験式（ヒル表記法）: C₁₃H₁₈N₄O₉
• CAS番号: 17388-80-6
• 分子量: 374.30
• MDL番号: MFCD31563062
• UNSPSCコード: 12352211
• UNSPSCコード: 12352200
• NACRES: NA.26

特性

• 由来生物: synthetic
• 品質水準: 200
• アッセイ: ≥95% (HPLC)
• フォーム: solid
• 色: white to beige
• mp: 130-135 °C
• 保管温度: 2-8°C
• SMILES記法: NC1=C(C(N[C@H](C(O)=O)CC(O)=O)=O)N=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2
• InChI: 1S/C13H18N4O9/c14-10-7(11(23)16-4(13(24)25)1-6(19)20)15-3-17(10)12-9(22)8(21)5(2-18)26-12/h3-5,8-9,12,18,21-22H,1-2,14H2,(H,16,23)(H,19,20)(H,24,25)/t4-,5+,8+,9+,12+/m0/s1

詳細

詳細

SAICAR (a ribotide) can lose its phosphate group leading to the appearance of a riboside known as succinylaminoimidazolecarboxamide riboside (SAICAriboside or SAICAr) in cerebrospinal fluid, in urine, and, to a lesser extent, in plasma. SAICAriboside is characteristic of ADSL, a heritable deficiency of the enzyme adenylosuccinate lyase (ASL or adenylosuccinase) responsible for metabolizing SAICAR (SZMP) to AICAR (ZMP) and adenylosuccinate (SAMP) to AMP. ASL deficiency causes increased SAICAR & SAMP, and their corresponding rephosphorylated products SAICAr & succinyladenosine (S-Ado).

保管および安定性

Heat sensitive

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable