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Merck

PHR2020

Supelco

Candesartan Cilexetil Related Compound F

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

(1-(Cyclohexyloxycarbonyloxy]ethyl 2-ethoxy-1-{[2′-(2-ethyl-2H-tetrazol-5-yl)-biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate

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About This Item

実験式(ヒル表記法):
C35H38N6O6
分子量:
638.71
UNSPSCコード:
41116107
NACRES:
NA.24

グレード

certified reference material
pharmaceutical secondary standard

品質水準

認証

traceable to USP 1087869

APIファミリー

candesartan

CofA

current certificate can be downloaded

包装

pkg of 20 mg

アプリケーション

pharmaceutical small molecule

フォーマット

neat

保管温度

2-8°C

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Candesartan cilexetil is a selective antagonist to Angiotensin II receptors, that plays a crucial role in blood pressure regulation and sodium homeostasis, and is popularly used for the treatment of hypertension, diabetic nephropathy and congestive heart failure.

アプリケーション

Candesartan cilexetil may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatographic techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAB4750 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

関連製品

製品番号
詳細
価格

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

PHR2020-20MG-PW:
PHR2020-20MG:


Choose from one of the most recent versions:

試験成績書(COA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

A comparison of the efficacy and duration of action of candesartan cilexetil and losartan as assessed by clinic and ambulatory blood pressure after a missed dose, in truly hypertensive patients: a placebo-controlled, forced titration study
Lacourciere Y and Asmar R
American Journal of Hypertension, 12(12), 1181-1187 (1999)
Determination of candesartan cilexetil in tablets by spectrofluorimetry
Sakur AA and Hanan F
International Journal of Pharmaceutical Sciences Review and Research, 4(2), 60-63 (2010)
Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist
Otsuka M, et al.
Thorax, 59(1), 31-38 (2004)
Characterization of conjugated metabolites of a new angiotensin II receptor antagonist, candesartan cilexetil, in rats by liquid chromatography/electrospray tandem mass spectrometry following chemical derivatization
Kondo T, et al.
Journal of Mass Spectrometry : Jms, 31(8), 873-878 (1996)
Q-Analysis Spectrophotometric methods for estimation of Candesartan Cilexetil and Hydrochlorothiazide in tablet dosage form
Jignesh P, et al.
Journal of Chemical and Pharmaceutical Research, 2(3), 10-14 (2010)

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