PHR1758

チオ尿素

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: スルホ尿素, チオカルバミド
• 化学式: NH₂CSNH₂
• CAS番号: 62-56-6
• 分子量: 76.12
• Beilstein: 605327
• EC Number: 200-543-5
• MDL番号: MFCD00008067
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823597
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• APIファミリー: propylthiouracil
• CofA: current certificate can be downloaded
• 包装: pkg of 200 mg
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 170-176 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: NC(N)=S
• InChI: 1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
• InChI Key: UMGDCJDMYOKAJW-UHFFFAOYSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiourea is a chaotropic agent or strong denaturant. It has been used to solubilize membrane and organelle specific proteins for analysis by two-dimensional gel electrophoresis. Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and UV-induced crosslinking of collagen. As a chelator of cuprous copper, thiourea inhibits this intermediate in oxidative reactions of cupric ion. This process afforded protection of bovine albumin from copper-mediated oxidative reactions.

アプリケーション

カオトロピック剤;強力な変性剤。タンパク質の溶解性と回収率を高めます。

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA8226 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS08,GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302,H351,H361fd,H411
• 注意書き: P202 - P264 - P270 - P273 - P301 + P312 - P308 + P313
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3