PHR1579

ウルソデオキシコール酸

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 3α,7β-ジヒドロキシ-5β-コラン-24-酸, 5β-コラン-24-酸-3α,7β-ジオール, 7β-ヒドロキシリトコール酸, UDCS
• 実験式（ヒル表記法）: C₂₄H₄₀O₄
• CAS番号: 128-13-2
• 分子量: 392.57
• Beilstein: 3219888
• EC Number: 204-879-3
• MDL番号: MFCD00003680
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823487
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. U0800000; traceable to USP 1707806
• APIファミリー: ursodiol
• CofA: current certificate can be downloaded
• 包装: pkg of 500 mg
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 203-204 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1
• InChI Key: RUDATBOHQWOJDD-UZVSRGJWSA-N
• 遺伝子情報: human ... NR1H4(9971)

詳細

詳細

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards

Ursodiol is an important bile acid, which can be biologically derived from the epimerization of chenodiol by intestinal bacteria. It is widely used in combination with chenodiol for gall stone dissolution and cholestatic liver diseases.

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Ursodiol may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using liquid chromatography technique with fluorigenic derivatization.

アナリシスノート

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC4017 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319
• 注意書き: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable