PHR1572

オキシメタゾリン 塩酸塩

certified reference material, pharmaceutical secondary standard

• 別名: 2-(3-ヒドロキシ-2,6-ジメチル-4-t-ブチルベンジル)-2-イミダゾリン 塩酸塩
• 実験式（ヒル表記法）: C₁₆H₂₄N₂O · HCl
• CAS番号: 2315-02-8
• 分子量: 296.84
• EC Number: 219-015-0
• MDL番号: MFCD00058147
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823480
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. O0290000; traceable to USP 1486004
• APIファミリー: oxymetazoline
• CofA: current certificate can be downloaded
• 包装: pkg of 10 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• InChI Key: BEEDODBODQVSIM-UHFFFAOYSA-N
• 遺伝子情報: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxymetazoline hydrochloride belongs to the category of non-selective adrenergic drugs commonly used as eye and nose drops.

アプリケーション

Oxymetazoline hydrochloride may be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations using spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

α_2A-アドレナリンレセプタ-の部分アゴニストです。5-HT_1A, 5-HT_1B, 5-HT_1Dセロトニンレセプタ-のアゴニストです。 5-HT_1Cセロトニンレセプタ-に対してはアゴニスト-アンタゴニストの両方の作用があります。

脚注

To see an example of a Certificate of Analysis for this material enter LRAB5024 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• ピクトグラム: GHS06,GHS05
• シグナルワード: Danger
• 危険有害性情報: H300 + H330,H318,H412
• 注意書き: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• 保管分類コード: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3