PHR1027

グアイフェネシン

certified reference material, pharmaceutical secondary standard

• 別名: グアヤコールグリセリンエーテル, 3-(o-メトキシフェノキシ)-1,2-プロパンジオール, グアイフェネシン, グリセロールグアイアコラート
• 実験式（ヒル表記法）: C₁₀H₁₄O₄
• CAS番号: 93-14-1
• 分子量: 198.22
• EC Number: 202-222-5
• MDL番号: MFCD00016873
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823057
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. G0700000; traceable to USP 1301007
• APIファミリー: guaifenesin
• CofA: current certificate can be downloaded
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: COc1ccccc1OCC(O)CO
• InChI: 1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3
• InChI Key: HSRJKNPTNIJEKV-UHFFFAOYSA-N

詳細

詳細

Guaifenesin is an expectorant, widely used in the treatment of cough. Its mode of action involves the alleviating of cough discomfort by increasing sputum volume and decreasing its viscosity, thus resulting in effective cough.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

Guaifenesin may be used as a reference standard in determining the concentration of guaifenesin present in pharmaceutical formulations and human plasma using colorimetric technique and high performance liquid chromatography (HPLC), respectively. It may also be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC3180 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable