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Merck

PHR1022

Supelco

Butylparaben

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

4-Hydroxybenzoic acid butyl ester

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About This Item

実験式(ヒル表記法):
C11H14O3
CAS番号:
分子量:
194.23
Beilstein:
1103741
EC Number:
MDL番号:
UNSPSCコード:
41116107
NACRES:
NA.24

グレード

certified reference material
pharmaceutical secondary standard

品質水準

認証

traceable to Ph. Eur. B1217000
traceable to USP 1084000

APIファミリー

parabens

CofA

current certificate can be downloaded

テクニック

HPLC: suitable
gas chromatography (GC): suitable

アプリケーション

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

フォーマット

neat

保管温度

2-30°C

InChI

1S/C11H14O3/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7,12H,2-3,8H2,1H3

InChI Key

QFOHBWFCKVYLES-UHFFFAOYSA-N

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詳細

Butylparaben is a compound, which belongs to the class of parabens.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

Butylparaben may be used as a reference standard for the determination of the analyte in cosmetics, food samples and human breast cancerous tissue by chromatography techniques.
Butylparaben may be used as an internal standard in the analysis of aspirin and warfarin in pharmaceutical formulations using reversed-phase high performance liquid chromatography (RP-HPLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

このような2次標準は、USP、EP(PhEur)、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAB7759 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

ピクトグラム

Corrosion

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Eye Dam. 1 - Skin Irrit. 2

保管分類コード

11 - Combustible Solids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

PHR1022-1G-PW:
PHR1022-10G:
87808-1G-BULK:
PHR1022-1G:
PHR1022-10G-PW:
87808-1G:
PHR1022-1G-BULK:


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試験成績書(COA)

Lot/Batch Number

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GC-MS method for the determination of paraben preservatives in the human breast cancerous tissue.
Shanmugam G, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 96(2), 391-396 (2010)
Development and validation of a reversed-phase liquid chromatographic method for analysis of aspirin and warfarin in a combination tablet formulation
Montgomery RE, et al.
Journal of Pharmaceutical and Biomedical Analysis, 15, 73-82 (1996)
Effects of butylparaben on the male reproductive system in rats
Oishi S
Toxicology and Industrial Health, 17, 31-39 (2001)
Anna Viridén et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 77(1), 99-110 (2010-11-18)
This study investigates the effect of the chemical heterogeneity of hydroxypropyl methylcellulose (HPMC) on the release of model drug substances from hydrophilic matrix tablets. The hypothesis was that the release of drug substances could be influenced by possible interactions with
Anuschka Liekens et al.
Journal of chromatography. A, 1218(38), 6654-6662 (2011-08-25)
The effect of the addition of 25%, 50% and 75% (weight percent, wt%) of larger particles (resp. 3 and 5 μm) to a commercial batch of 1.9 μm particles has been investigated as an academic exercise to study the effects

プロトコル

Separation of Methyl Paraben, analytical standard; Ethylparaben, United States Pharmacopeia (USP) Reference Standard; Propylparaben, United States Pharmacopeia (USP) Reference Standard; Butylparaben, United States Pharmacopeia (USP) Reference Standard

Separation of Methyl Paraben, analytical standard; Ethylparaben, United States Pharmacopeia (USP) Reference Standard; Propylparaben, United States Pharmacopeia (USP) Reference Standard; Butylparaben, United States Pharmacopeia (USP) Reference Standard

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