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Merck
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主要文書

B0470000

Benperidol

European Pharmacopoeia (EP) Reference Standard

別名:

1-{1-[4-(4-Fluorophenyl)-4-oxobutyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one

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About This Item

実験式（ヒル表記法）:
C22H24FN3O2
CAS番号:
2062-84-2
分子量:
381.44
UNSPSCコード:
41116107
NACRES:
NA.24

グレード

pharmaceutical primary standard

APIファミリー

benperidol

メーカー／製品名

EDQM

アプリケーション

pharmaceutical (small molecule)

フォーマット

neat

保管温度

2-8°C

InChI

1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28)

InChI Key

FEBOTPHFXYHVPL-UHFFFAOYSA-N

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詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

Benperidol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

この製品は発行元の薬局方による供給としてお届けします。現在の単位量については、EDQM reference substance catalogueをご覧ください。

その他情報

Sales restrictions may apply.

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試験成績書（COA）

Lot/Batch Number

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文書ライブラリにアクセスする

Jo Ann V Antenor-Dorsey et al.
European journal of nuclear medicine and molecular imaging, 35(4), 771-778 (2007-12-12)
N-([(11)C]methyl)benperidol ([(11)C]NMB) can be used for positron emission tomography (PET) measurements of D(2)-like dopamine receptor binding in vivo. We report the absorbed radiation dosimetry of i.v.-administered (11)C-NMB, a critical step before applying this radioligand to imaging studies in humans. Whole-body
S Leucht et al.
The Cochrane database of systematic reviews, (1)(1), CD003083-CD003083 (2002-03-01)
Benperidol is a relatively old antipsychotic drug, marketed since 1966, used in Germany for 30 years, but also available in Belgium, Greece, Italy, the Netherlands and the UK. Benperidol is a butyrophenone antipsychotic, with the highest neuroleptic potency in terms
S M Moerlein et al.
Nuclear medicine and biology, 24(4), 311-318 (1997-05-01)
Radiation absorbed doses due to IV administration of [18F](N-methyl) benperidol ([18F]NMB) were estimated by whole-body PET imaging of nonhuman primates. Time-activity curves were obtained for nine compartments (striatum, eyes, heart, lungs, liver, gallbladder, intestines, kidneys, bladder) by using dynamic PET
O Gruber et al.
Der Nervenarzt, 71(1), 30-37 (2000-03-01)
In this study, we investigated experimentally the effects of different activation procedures on both motor and psychic symptoms in of 11 in-patients with acute neuroleptic-induced akathisia using the Hillside and Barnes akathisia rating scales and videotape rating technique. Motor activation
Susanne Nikolaus et al.
European journal of nuclear medicine and molecular imaging, 30(3), 390-395 (2003-03-14)
Unilateral destruction of the substantia nigra by local application of 6-hydroxydopamine (6-OHDA) serves as an animal model for Parkinson's disease. In this study, the changes in neostriatal dopamine D(2) receptor density were investigated with a small animal positron emission tomograph
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