ALD00602

(–)-PSI Reagent

95%

• 別名: (2S,3aS,6R,7aS)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide, (–)-Ψ, Phosphorus-Sulfur Incorporation Reagent
• 実験式（ヒル表記法）: C₁₆H₁₆F₅OPS₃
• CAS番号: 2245335-70-8
• 分子量: 446.46
• UNSPSCコード: 12352101
• NACRES: NA.22

特性

• アッセイ: 95%
• 形状: powder or crystals
• mp: 103-107 °C

詳細

アプリケーション

Air- and moisture-tolerant, this (-)-PSI Reagent was developed in the Baran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (+)-PSI Reagent, is also available (cat# ALD00604).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).

Learn more about PI and PSI reagents

その他情報

Unlocking P(V): Reagents for chiral phosphorothioate synthesis

PSI on OpenFlask

法的情報

PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable