91503

パルミトイル-L-カルニチン

analytical standard

• 別名: (2R)-3-カルボキシ-N,N,N-トリメチル-2-[(1-オキソヘキサデシル)オキシ]-1-プロパンアミニウム 分子内塩, L-カルニチンヘキサデカノイルエステル, C16-カルニチン, ヘキサデカノイル-L-カルニチン
• 実験式（ヒル表記法）: C₂₃H₄₅NO₄
• CAS番号: 2364-67-2
• 分子量: 399.61
• Beilstein: 4152034
• MDL番号: MFCD00152152
• UNSPSCコード: 41116107
• NACRES: NB.21

特性

• グレード: analytical standard
• 品質水準: 100
• アッセイ: ≥95.0% (HPLC)
• 光学活性: [α]/D -17.0±2.0°, c = 1 in methanol
• シェルフライフ: limited shelf life, expiry date on the label
• 不純物: ≤10% water
• アプリケーション: clinical testing
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O
• InChI: 1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3/t21-/m1/s1
• InChI Key: XOMRRQXKHMYMOC-OAQYLSRUSA-N

詳細

詳細

Palmitoyl-L-carnitine (PLC) belongs to the class of long chain acylcarnitine compounds. It is an acyl-chain ester, which can be obtained from L-carnitine via acylcarnitine family transferase. PLC is reported to be used for the phospholipid reacylation in erythrocyte membrane ghosts.

アプリケーション

Palmitoyl-L-carnitine may be used as an analytical standard to quantify the analyte in biological samples of patients with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS). The feasibility of adding L-carnitine to the peritoneal dialysis (PD) solution in APD-treated end-stage renal disease patients is investigated. It may also be used as an analytical reference standard for the separation and identification of underivatized palmitoyl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).

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安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable