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cell analysis
詳細
Glioblastoma multiforme is the most common and malignant primary brain tumor in adults, with a high recurrence rate and a five-year survival rate of less than 5% (1). Nearly 50% of glioblastomas originate in the frontal or temporal lobes of the brain (1). Glioblastomas are the most aggressive form of cancer and demonstrate a high degree of chemotherapy resistance, highlighting the importance of relevant human patient-derived cell models for advancing research into characteristics and treatment of this disease.
SF295 is a patient-derived glioblastoma cell line originating from a temporal lobe tumor (2). SF295 cells do not express the glial markers GFAP or glutamine synthetase, but have been shown to positively express neurofibromin-1, identified as one of the most frequently mutated factors in glioblastoma multiforme (3). SF295 cells exhibit hypertriploidy and glial-like morphology in culture and are non-tumorigenic in athymic mice (2). The SF295 cell line is highly published in studies of chemotherapeutic treatments for glioblastoma, representing a valuable cellular model for assessment of drugs and molecular modulators for their effect on glioblastomas.
<bold>Source:</bold>
The SF295 glioblastoma cell line was derived from the left frontal lobe tumor of a 67-year-old female patient (2).
Research Category:
Cancer
SF295 is a patient-derived glioblastoma cell line originating from a temporal lobe tumor (2). SF295 cells do not express the glial markers GFAP or glutamine synthetase, but have been shown to positively express neurofibromin-1, identified as one of the most frequently mutated factors in glioblastoma multiforme (3). SF295 cells exhibit hypertriploidy and glial-like morphology in culture and are non-tumorigenic in athymic mice (2). The SF295 cell line is highly published in studies of chemotherapeutic treatments for glioblastoma, representing a valuable cellular model for assessment of drugs and molecular modulators for their effect on glioblastomas.
<bold>Source:</bold>
The SF295 glioblastoma cell line was derived from the left frontal lobe tumor of a 67-year-old female patient (2).
Research Category:
Cancer
細胞株の由来
Human, Cancer Cells
包装
≥1X106 cells/vial
保管および安定性
Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
その他情報
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@emdmillipore.com.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
212.0 °F
引火点(℃)
100 °C
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SCC289:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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