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Merck

SCC069

Sigma-Aldrich

HSC-T6 Rat Hepatic Stellate Cell Line

Rat

別名:

HSC, Perisinusoidal cells, Ito cells, Hepatic lipocytes, Hepatic pericytes

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About This Item

UNSPSCコード:
41106514
eCl@ss:
32011203
NACRES:
NA.81

product name

HSC-T6 Rat Hepatic Stellate Cell Line, The HSC-T6 rat hepatic stellate cell line is a valuable cell model for studies of retinoid metabolism based on their similar retinoid phenotype as primary cells.

由来生物

rat

品質水準

テクニック

cell based assay: suitable
cell culture | mammalian: suitable

輸送温度

ambient

詳細

Hepatocytes and hepatic stellate cells play important roles in retinoid uptake, storage, mobilization and metabolism. Hepatic stellate cells represent only 5-7% of the total cells present in the liver. Isolation of primary stellate cells is thus time-consuming and often accompanied by low yields and considerable lot-to-lot variations. HSC-T6 Rat Hepatic Stellate Cell Line is an immortalized line isolated from SV40 large T-antigen transformed primary stellate cells of male Sprague-Dawley retired breeder rats. HSC-T6 Rat Hepatic Stellate Cell line is a useful model for the study of hepatic retinoid storage and metabolism.

細胞株の説明

Hepatocyte Cells

アプリケーション

Research Category
代謝

感染症

炎症及び免疫

幹細胞研究
Research Sub Category
肝生理学
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@emdmillipore.com.

構成

1) ≥1X106 viable HSC-T6 Rat Hepatic Stellate Cells: (Catalog No. SCC069). Store in liquid nitrogen.

品質

• Each vial contains ≥ 1X106 viable cells.
• Cells tested negative for infectious diseases by a Mouse/Rat Comprehensive CLEAR panel PCR panel by Charles River Animal Diagnostic Services.
• Cells tested negative for mycoplasma contamination.

保管および安定性

HSC-T6 Rat Hepatic Stellate Cells should be stored in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

保管分類コード

10 - Combustible liquids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

SCC069:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Ryuichi Noguchi et al.
Molecular medicine reports, 22(4), 2948-2956 (2020-09-19)
An orally bioavailable small molecule inhibitor of plasminogen activator inhibitor‑1 (PAI‑1) is currently being clinically assessed as a novel antithrombotic agent. Although PAI‑1 is known to serve a key role in the pathogenesis of metabolic syndrome (MetS) including nonalcoholic steatohepatitis
Jiunn-Sheng Wu et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 8426051-8426051 (2020-07-28)
Hepatic stellate cell (HSC) activation is a vital driver of liver fibrosis. Recent research efforts have emphasized the clearance of activated HSCs by apoptosis, senescence, or reversion to the quiescent state. LPS induces human HSC activation directly and contributes to
Hongxia Liang et al.
ACS nano, 12(7), 6536-6544 (2018-06-27)
Acute liver failure is a critical condition characterized by global hepatocyte death and often time needs a liver transplantation. Such treatment is largely limited by donor organ shortage. Stem cell therapy offers a promising option to patients with acute liver

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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