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詳細
Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-1 mouse myeloma cells. Recognizes the ~105 kDa Rb protein.
Recognizes the ~105 kDa Rb protein. Sold under license of U.S. Patent 5,853,988 and corresponding patents.
This Anti-Rb (Ab-5) Mouse mAb (LM95.1) is validated for use in Immunoblotting, Paraffin Sections for the detection of Rb (Ab-5).
免疫原
Epitope: within a 56 kDa C-terminal fragment
Human
recombinant, human Rb
アプリケーション
Immunoblotting (1 µg/ml; see application references)
Paraffin Sections (3 µg/ml, see comments and application references)
Paraffin Sections (3 µg/ml, see comments and application references)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
物理的形状
In 50 mM sodium phosphate buffer, 0.2% gelatin.
アナリシスノート
Negative Control
Saos cells
Saos cells
Positive Control
ML-1 cells or normal colon tissue
ML-1 cells or normal colon tissue
その他情報
Dyson, N., et al. 1992. J. Virol.66, 4606.
Dyson, N., et al. 1990. J. Virol.64, 1353.
Horowitz, J.M., et al. 1989. Science243, 937.
Whyte, P., et al. 1988. Nature334, 124.
Klein, G. 1987. Science238, 1539.
Lee, W.H., et al. 1987. Science235, 1394.
Lee, W.H., et al. 1987. Nature329, 642.
Knudson, A.G. 1971. Proc. Natl. Acad. Sci. USA68, 820.
Dyson, N., et al. 1990. J. Virol.64, 1353.
Horowitz, J.M., et al. 1989. Science243, 937.
Whyte, P., et al. 1988. Nature334, 124.
Klein, G. 1987. Science238, 1539.
Lee, W.H., et al. 1987. Science235, 1394.
Lee, W.H., et al. 1987. Nature329, 642.
Knudson, A.G. 1971. Proc. Natl. Acad. Sci. USA68, 820.
Pre-treatment with heat or pressure cooker may improve staining of some tissue specimens; this should be determined for each specimen. Antibody should be titrated for optimal results in individual systems.
法的情報
Sold under license of U.S. Patent 5,853,988 and corresponding patents.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
11 - Combustible Solids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
OP66-100UG:
OP66-ML:
OP66-MG:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Abstracts from USCAP 2019: Genitourinary Pathology (including renal tumors) (776-992).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 32(Suppl 2), 1-173 (2019-03-20)
Alessandro Bertolo et al.
Scientific reports, 10(1), 19084-19084 (2020-11-07)
Mesenchymal stromal cells (MSC) are used in cell therapy, but results depend on the unknown quality of cell populations. Extended culture time of MSC increases their senescent levels, leading to a critical loss of cell fitness. Here, we tested the
Ching-Wen Tsai et al.
Artificial cells, nanomedicine, and biotechnology, 46(8), 1852-1863 (2017-10-31)
This study evaluated the effect of chitosan, poly vinyl alcohol (PVA) and poly (2-hydroxyethyl methacrylate) (pHEMA) on delaying the human fibroblast senescence. Cells could form suspending multicellular spheroids on these biomaterials, but only chitosan was capable of decreasing the SA
Tao Wei et al.
mBio, 12(4), e0227721-e0227721 (2021-09-02)
The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous cell carcinomas in laboratory mice.
Hsi-Hsien Hsieh et al.
Journal of cell science, 130(19), 3272-3281 (2017-08-11)
SerpinB2 is a serine protease inhibitor also known as plasminogen activator inhibitor type 2 (PAI-2). It has been well documented that serpinB2 is an inhibitor of urokinase plasminogen activator (uPA) and tissue plasminogen activator (tPA). Interestingly, serpinB2 levels are increased
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