MABN48

Anti-UCHL1 Antibody, clone MCA-BH7

clone MCA-BH7, from mouse

• 別名: Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: MCA-BH7, monoclonal
• 化学種の反応性: human, bovine, rat
• テクニック: immunofluorescence: suitable; western blot: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_004172
• UniProtアクセッション番号: P09936
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... UCHL1(7345)

詳細

詳細

Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1), a thiol protease belonging to the peptidase C12 family, is involved in the processing of ubiquitin precursors and of ubiquitinated proteins. UCH-L1 recognizes and hydrolyzes peptide bonds at the C-termial glycine of ubiquitin. UCH-L1 is expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Defects in UCH-L1 are the cause of Parkinson disease type 5.

免疫原

His-tagged recombinant protein corresponding to human UCHL1.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
神経変性疾患

Detect UCH-L1 using this mouse monoclonal antibody, Anti-UCHL1 Antibody, clone MCA-BH7 validated for use in western blotting & Immunofluorescence.

Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected UCHL1 in 10 µg of human brain tissue lysate.

Immunofluorescence Analysis: A 1:2,000 dilution from a representative lot detected UCHL1 in rat brain spinal cord tissue (Gerry Shaw. EnCor Biotechnology, Inc., Gainesville, Florida).

品質

Evaluated by Western Blotting in rat brain spinal cord tissue lysate.

Western Blotting Analysis: A 1:2,000 dilution of this antibody detected UCHL1 in 10 µg of rat brain tissue lysate.

ターゲットの説明

~25 kDa observed

物理的形状

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives.

保管および安定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

アナリシスノート

Control
Rat brain spinal cord tissue lysate.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable