MABF473

Anti-Ly-6G (Gr-1) Antibody (mouse), PE-Cy7, clone RB6-8C5

clone RB6-8C5, 0.2 mg/mL, from rat

• 別名: Lymphocyte antigen 6G, Ly-6G, Ly-6G.1
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rat
• 品質水準: 100
• 結合体: PE-Cy7
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: RB6-8C5, monoclonal
• 化学種の反応性: mouse
• 濃度: 0.2 mg/mL
• テクニック: flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• アイソタイプ: IgG2bκ
• UniProtアクセッション番号: P35461
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Ly6G(546644)

詳細

詳細

The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes.Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports sµggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. Cytometry A, 58(2): 195-200.

This rat monoclonal antibody Anti-Ly-6G (Gr-1) (mouse), PE-Cy7, clone RB6-8C5 validated for use in IHC, Flow Cytometry & IP for the detection of Ly-6G (Gr-1).

品質

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 µg of this antibody detected Ly-6G (Gr-1) in one million C57Bl/6 bone marrow cells.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable