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由来生物
mouse
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
DCS-35, monoclonal
交差性
mouse, pig, rat, human
メーカー／製品名
Chemicon®
テクニック
activity assay: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
アイソタイプ
IgG1κ
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CDK4(1019)
rat ... Cdk4(94201)
詳細
The prototype of the cdk family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression.
特異性
Recognizes a 34 kDa protein identified as p34 or cyclin-dependent kinase 4 (cdk4). It shows no cross-reaction with other cdks.
免疫原
Raised against purified recombinant cdk4 protein.
アプリケーション
Research Category
エピジェネティクス及び核内機能分子
エピジェネティクス及び核内機能分子
Research Sub Category
細胞周期、DNA複製及び修復
細胞周期、DNA複製及び修復
Detect Cdk4 with Anti-Cdk4 Antibody, clone DCS-35 (Mouse Monoclonal Antibody), that has been shown to work in IF, IP, EA, WB & IHC.
Immunofluorescence
Immunoprecipitation: excellent for coprecipitation of D-type cyclins bound to cdk4.
Western Blotting: 2-4 ug/mL
Kinase Assay
The prototype of the cdk family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression.
Optimal working dilutions must be determined by the end user.
Immunoprecipitation: excellent for coprecipitation of D-type cyclins bound to cdk4.
Western Blotting: 2-4 ug/mL
Kinase Assay
The prototype of the cdk family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression.
Optimal working dilutions must be determined by the end user.
関連事項
Replaces: MABE548
物理的形状
Format: Purified
Purified immunoglobulin. Liquid containing 10 mM PBS, pH 7.4 with 0.2% BSA and 0.09% sodium azide.
保管および安定性
Maintain liquid material at 2-8°C for up to 24 months.
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
The immunohistochemical profile of the primary and metastatic carcinoma of the clitoris: a case report.
Andrzej Semczuk, Danuta Skomra, Katarzyna Jankiewicz, Aneta Adamiak, Elzbieta Korobowicz et al.
Archives of Gynecology and Obstetrics null
Effect of extracts from Radix Ginseng, Radix Notoginseng and Rhizoma Chuanxiong on delaying aging of vascular smooth muscle cells in aged rats.
Li-Li Tao,Yan Lei,Guo-Li Wang,Ling-Qun Zhu,Yang Wang
Chinese Journal of Integrative Medicine null
Cell cycle regulators cyclin D1 and CDK4/6 have estrogen receptor-dependent divergent functions in breast cancer migration and stem cell-like activity.
Lamb, R; Lehn, S; Rogerson, L; Clarke, RB; Landberg, G
Cell Cycle null
Effects of quercetin on CDK4 mRNA and protein expression in A549 cells infected by H1N1.
Wan, Q; Wang, H; Lin, Y; Gu, L; Han, M; Yang, Z; Zhang, Y; Ma, R; Wang, L; Wang, Z
Biomedical Reports null
Expression of the cell-cycle regulatory proteins (pRb, cyclin D1, p16INK4A and cdk4) in human endometrial cancer: correlation with clinicopathological features.
Andrzej Semczuk, Roman Miturski, Danuta Skomra, Jerzy A Jakowicki
Archives of Gynecology and Obstetrics null
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