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Merck
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資料

安全性情報

MAB8703

Sigma-Aldrich

Anti-Dengue Virus Type III Antibody, clone 5D4-11

clone 5D4-11, Chemicon®, from mouse

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41

由来生物

mouse

品質水準

抗体製品の状態

purified antibody

クローン

5D4-11, monoclonal

化学種の反応性

human

メーカー/製品名

Chemicon®

テクニック

immunofluorescence: suitable

アイソタイプ

IgG1

輸送温度

wet ice

詳細

Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.

特異性

Reacts with the Dengue type 3 virus.

免疫原

Dengue virus antigens (H87).

アプリケーション

Research Category
感染症
Research Sub Category
感染症-ウイルス
Anti-Dengue Virus Type III Antibody, clone 5D4-11 is an antibody against Dengue Virus Type III for use in IF.
Immunofluorescent assay.

Final working dilutions must be determined by end user.

物理的形状

Format: Purified
Purified. 0.02M Phosphate Buffer, pH 7.6, 0.25M NaCl and 0.1% sodium azide.

保管および安定性

Maintain at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

MAB8703:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Evaluation by flow cytometry of antibody-dependent enhancement (ADE) of dengue infection by sera from Thai children immunized with a live-attenuated tetravalent dengue vaccine.
Bruno Guy, Pornthep Chanthavanich, Sophie Gimenez, Chukiat Sirivichayakul et al.
Vaccine null
Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies.
Gentry, M K, et al.
The American Journal of Tropical Medicine and Hygiene, 31, 548-555 (1982)
Dengue virus-specific and flavivirus group determinants identified with monoclonal antibodies by indirect immunofluorescence
Henchal, E A, et al
The American Journal of Tropical Medicine and Hygiene, 31, 830-836 (1982)

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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