MAB345A4

Anti-O4 Antibody, clone 81, Alexa Fluor^™488 Conjugate

clone 81 (mAB 04), from mouse, ALEXA FLUOR^™ 488

• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: ALEXA FLUOR^™ 488
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 81 (mAB 04), monoclonal
• 化学種の反応性: rat
• 化学種の反応性（ホモロジーによる予測）: human (based on 100% sequence homology), bovine (based on 100% sequence homology), chicken (based on 100% sequence homology), mouse (based on 100% sequence homology)
• テクニック: immunocytochemistry: suitable
• アイソタイプ: IgM
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Oligodendrocytes and astrocytes are derived from common precursor cells, glioblasts (Sommer, 1981). O-Antigens are sulfatides, which function as differentiation markers on the surface of oligodendrocytes of the central nervous system. O4 is formed postnatally (Schachner, 1981) and is a marker for cell bodies and processes of oligodendrocytes types I and II (hairy eyeball type). During oligodendrocyte differentiation, O4 occurs in pro-oligodendrocytes, but not in O-2A-progenitor cells. O4 occurs from day 3 onwards in cell cultures of embryonic mouse brain. Anti-O4 can be used in myelination, demyelination and remyelination studies and in regeneration experiments.

特異性

This antibody recognizes Oligodendrocyte marker O4. Also reacts with certain galactolipids in sperm.

免疫原

Homogenate of white matter of corpus callosum from bovine brain.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
神経変性疾患

Anti-O4 Antibody, clone 81, Alexa Fluor^™488 Conjugate detects level of O4 & has been published & validated for use in ICC.

品質

Evaluated by Immunocytochemistry in undifferentiated rat oligodendrocyte precursor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected O4 in undifferentiated rat oligodendrocyte precursor cells.

物理的形状

Precipitation followed by ion exchange purification

Purified mouse monoclonal IgM conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

保管および安定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

アナリシスノート

Control
Undifferentiated rat oligodendrocyte precursor cells

法的情報

ALEXA FLUOR is a trademark of Life Technologies

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable