MAB2609

Anti-beta Arrestin 1 Antibody, clone 3H11.2

clone 3H11.2, from mouse

• 別名: Retinal S-antigen, Rod photoreceptor arrestin, S-antigen, retina and pineal gland (arrestin), arrestin 1, retinal S-antigen (48 KDa protein)
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: saturated ammonium sulfate (SAS) precipitated
• 抗体製品タイプ: primary antibodies
• クローン: 3H11.2, monoclonal
• 化学種の反応性: human
• テクニック: immunofluorescence: suitable; western blot: suitable
• アイソタイプ: IgMκ
• NCBIアクセッション番号: NP_004032.2
• UniProtアクセッション番号: P49407
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ARRB1(408)

詳細

詳細

The Arrestin family consists of four members: Arrestin 1 (visual Arrestin), Arrestin 2 (beta Arrestin 1), Arrestin 3 (beta Arrestin 2), and Arrestin 4 (cone Arrestin). While visual and cone Arrestins are found almost exclusively in the retina, beta Arrestins 1 and 2 are ubiquitously expressed. Beta Arrestins appear to act as negative regulators on G protein-coupled receptors, (Lefkowitz, 1998). Interaction with molecules such as clathrin, AP-2 and NSF directs the clathrin-mediated internalization of G-protein-coupled receptors. Interaction with molecules such as Src, Raf, Erk, ASK1 and JNK3 appears to regulate several pathways that result in the activation of MAP kinases, (Lin, 1998; Miller, 2001).

特異性

Other species have not been tested.

Reacts with human beta-arrestin 1.

免疫原

Epitope: a.a. 357-372

KLH conjugated synthetic peptide corresponding to amino acids 357-372 of human beta arrestin 1.

アプリケーション

Research Category
細胞骨格

Research Sub Category
感覚・末梢神経

Gタンパク質

Anti-beta Arrestin 1 Antibody, clone 3H11.2 detects level of beta Arrestin 1 & has been published & validated for use in WB & IF.

品質

Evaluated on a representative lot by Western blot in HEK293 cell lysate.

ターゲットの説明

~47 kDa

物理的形状

Format: Purified

Purified in PBS with 0.05% NaN3.

保管および安定性

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

アナリシスノート

Control
HEK293 cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable