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Merck

HCVD3MAG-67K

Millipore

MILLIPLEX® Human Cardiovascular Disease (Acute Phase) Magnetic Bead Panel 3 - Cardiovascular Disease Multiplex Assay

The analytes available for this multiplex kit are: Adipsin, AGP, α2-Macroglobulin, CRP, Fetuin A, Fibrinogen, L-Selectin, Serum Amyloid P, Haptoglobin, & Platelet Factor-4.

別名:

human CVD APP immunoassay panel, luminex human cardiovascular disease acute phase proteins multiplex assay, millipore human CVD acute phase proteins multiplex kit

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質水準

化学種の反応性

human

メーカー/製品名

Milliplex®

assay range

accuracy: 102%
(Haptoglobin)

accuracy: 109%
(AGP)

accuracy: 113%
(Platelet Factor-4)

accuracy: 117%
(Adipsin)

standard curve range: 0.004-15 ng/mL
(L-Selectin & SAP)

standard curve range: 0.012-50 ng/mL
(CRP)

standard curve range: 0.037-150 ng/mL
(PF4)

standard curve range: 0.061-250 ng/mL
(HPTGN)

standard curve range: 0.098-400 ng/mL
(AGP & Adipsin)

standard curve range: 0.244-1,000 ng/mL
(Fetuin A & vWF)

standard curve range: 0.488-2,000 ng/mL
(A2M)

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Cardiovascular disease, particularly atherosclerotic vascular disease, is a leading cause of global mortality, accounting for 30% of all global deaths (WHO, 2010). Inflammatory mechanisms play a vital role in the initiation, maintenance, and progression of vascular disease with a strong correlation between inflammatory markers and prognosis in acute and chronic coronary artery disease. Numerous studies have demonstrated an association of obesity and diabetes with cardiovascular risk factors.

MILLIPLEX® Human Cardiovascular Disease (CVD) Panel 3 (Acute Phase) is a 10-plex kit to be used for the simultaneous quantification of any or all of the following analytes in human serum, plasma or tissue/cell lysate and culture supernatant samples: Adipsin, α-1-Acid-Glycoprotein (AGP), α-2-Macroglobulin (A2M), C Reactive Protein (CRP), Fetuin A, Fibrinogen, L-Selectin, Serum Amyloid P (SAP), Haptoglobin, and Platelet Factor-4 (PF4). (Please note: Fibrinogen is not detectable in serum.) This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

アプリケーション

  • Analytes: α-1 Acid Glycoprotein (AGP), α-2-Macroglobulin (A2M), Adipsin (Factor D), C Reactive Protein (CRP), Fetuin A, Fibrinogen, Haptoglobin, sL-Selectin, Platelet Factor-4 (PF4/CXCL4), Serum Amyloid P (SAP)
  • Recommended Sample Type: Human serum, plasma, cell/tissue culture supernatants and lysates
  • Recommended Sample Dilution: 25 μL per well of 1:40,000 diluted serum or plasma; tissue/cell culture samples may require dilution in appropriate control medium
  • NOTE: Fibrinogen is not detectable in serum
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C or 2 hours at room temperature (20-25 °C)
  • Research Category: Cardiovascular Disease
  • Research Subcategory: Metabolic Disorders

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

その他情報

Please contact Technical Service for linearity of dilution.
Sensitivity: See kit protocol for individual analyte sensitivity.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

ピクトグラム

Skull and crossbonesEnvironment

シグナルワード

Danger

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

ターゲットの組織

Respiratory system

保管分類コード

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

HCVD3MAG-67K-08:
HCVD3MAG-67K-10:
HCVD3MAG-67K-07:
HCVD3MAG-67K-04:
HCVD3MAG-67K-11:
HCVD3MAG-67K-02:
HCVD3MAG-67K-03:
HCVD3MAG-67K-09:
HCVD3MAG-67K-06:
HCVD3MAG-67K:
HCVD3MAG-67K-01:
HCVD3MAG-67K-05:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes.
Woodson, SE; Freiberg, AN; Holbrook, MR
Virus Research null
Jung Soo Lim et al.
Endocrinology and metabolism (Seoul, Korea), 31(4), 567-576 (2016-11-12)
Oxidative stress in primary aldosteronism (PA) is thought to worsen aldosterone-induced damage by activating proinflammatory processes. Therefore, we investigated whether inflammatory markers associated with oxidative stress is increased with negative impacts on heart function as evaluated by echocardiography in patients
Shao-Chun Wu et al.
Journal of inflammation research, 14, 3739-3753 (2021-08-17)
Severe trauma may lead to the systemic release of inflammatory mediators into the circulation with profound acute-phase responses; however, the understanding of the expression of these mediators remains limited. This study aimed to characterize the alterations in the expression of
Kévin Contrepois et al.
Cell, 181(5), 1112-1130 (2020-05-30)
Acute physical activity leads to several changes in metabolic, cardiovascular, and immune pathways. Although studies have examined selected changes in these pathways, the system-wide molecular response to an acute bout of exercise has not been fully characterized. We performed longitudinal
Julia E Herrmann et al.
Toxicology and applied pharmacology, 274(2), 302-312 (2013-11-30)
Human response to isoproterenol induced cardiac injury was evaluated by gene and protein pathway changes in human heart slices, and compared to rat heart slices and rat heart in vivo. Isoproterenol (10 and 100μM) altered human and rat heart slice

関連コンテンツ

Learn about biomarkers of cardiovascular disease (CVD) and discover how multiplex CVD panels, such as MILLIPLEX® multiplex assays, are being used to increase the efficiency of biomarker discovery for CVD research.

心血管疾患(CVD)バイオマーカーの詳細を確認し、MILLIPLEX® マルチプレックスアッセイのようなマルチプレックスCVDパネルを用いて、CVD研究のバイオマーカー探索の効率を高める方法をご覧ください。

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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