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Merck

HCVD1MAG-67K

Millipore

MILLIPLEX® Human Cardiovascular Disease (CVD) Magnetic Bead Panel 1 - Cardiovascular Disease Multiplex Assay

The analytes available for this multiplex kit are: BNP, NT-proBNP, CK-MB, CXCL6/GCP-2, CXCL16, Endocan-1 (ESM-1), FABP3, FABP4, LIGHT, Oncostatin (OSM), Placental Growth Factor (PlGF), Troponin I (TnI).

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質水準

化学種の反応性

human

メーカー/製品名

Milliplex®

assay range

accuracy: 100%
(CK-MB)

accuracy: 102%
(LIGHT)

accuracy: 102%
(Oncostatin (OSM))

accuracy: 103%
(CXCL6/GCP-2)

accuracy: 96%
(FABP3)

accuracy: 96%
(Placental Growth Factor (PlGF))

accuracy: 97%
(NT proBNP)

standard curve range: 137.2-100,000 pg/mL
(FABP3)

standard curve range: 2.7-2,000 pg/mL
(Placental Growth Factor (PlGF))

standard curve range: 34.3-25,000 pg/mL
(NT proBNP, CXCL16, Endocan-1 (ESM-1), LIGHT)

standard curve range: 6.9-5,000 pg/mL
(CXCL6, Oncostatin (OSM))

standard curve range: 68.6-50,000 pg/mL
(BNP, CK-MB, Troponin I (TnI))

standard curve range: 685.9-500,000 pg/mL
(FABP4)

inter-assay cv: <20%
intra-assay cv: <10%

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Cardiovascular disease, particularly atherosclerotic vascular disease, is a leading cause of global mortality, accounting for 30% of all global deaths (WHO, 2010). Inflammatory mechanisms play a vital role in the initiation, maintenance, and progression of vascular disease with a strong correlation between inflammatory markers and prognosis in acute and chronic coronary artery disease. Numerous studies have demonstrated an association of obesity and diabetes with cardiovascular risk factors.

The MILLIPLEX® Human Cardiovascular Disease (CVD) Panel 1 is a 12-plex kit to be used for the simultaneous quantification of any or all of the following analytes in human serum, plasma, or tissue/cell lysate and culture supernatant samples: BNP, NTproBNP, CK-MB, CXCL6, CXCL16, Endocan-1 (ESM-1), FABP3, FABP4, LIGHT, Oncostatin-M (OSM), Placental Growth Factor (PlGF), and Troponin I. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

特異性

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

アプリケーション

  • Analytes: BNP, CK-MB, CXCL6/GCP-2, CXCL16, Endocan-1 (ESM-1), FABP3, FABP4, LIGHT, NT-proBNP, Oncostatin M (OSM), Placental Growth Factor (PlGF), Troponin I (TnI)
  • Recommended Sample Type: Human serum, plasma, or tissue/cell culture supernatants and lysates
  • Recommended Sample Dilution: 25 μL per well of undiluted serum or plasma; tissue/cell culture samples may require dilution in appropriate control medium
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Cardiovascular Disease
  • Research Subcategory: Metabolic Disorders

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

その他情報

Please contact Technical Service for linearity of dilution.
Sensitivity: See kit protocol for individual analytes sensitive’s.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

ピクトグラム

Health hazardCorrosionExclamation markEnvironment

シグナルワード

Danger

危険有害性の分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

ターゲットの組織

Respiratory Tract

保管分類コード

10 - Combustible liquids


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

HCVD1MAG-67K-01:
HCVD1MAG-67K-06:
HCVD1MAG-67K-09:
HCVD1MAG-67K-12:
HCVD1MAG-67K-03:
HCVD1MAG-67K-05:
HCVD1MAG-67K:
HCVD1MAG-67K-07:
HCVD1MAG-67K-04:
HCVD1MAG-67K-10:
HCVD1MAG-67K-11:
HCVD1MAG-67K-08:
HCVD1MAG-67K-02:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Kévin Contrepois et al.
Cell, 181(5), 1112-1130 (2020-05-30)
Acute physical activity leads to several changes in metabolic, cardiovascular, and immune pathways. Although studies have examined selected changes in these pathways, the system-wide molecular response to an acute bout of exercise has not been fully characterized. We performed longitudinal
Amit Saxena et al.
Journal of the American College of Cardiology, 66(8), 930-939 (2015-08-22)
Cardiac manifestations of neonatal lupus (cardiac NL) include congenital heart block and cardiomyopathy. Several candidate biomarkers were evaluated in cases at risk for cardiac NL on the basis of potential roles in inflammation, fibrosis, and cardiac dysfunction: C-reactive protein (CRP);

関連コンテンツ

Learn about biomarkers of cardiovascular disease (CVD) and discover how multiplex CVD panels, such as MILLIPLEX® multiplex assays, are being used to increase the efficiency of biomarker discovery for CVD research.

心血管疾患(CVD)バイオマーカーの詳細を確認し、MILLIPLEX® マルチプレックスアッセイのようなマルチプレックスCVDパネルを用いて、CVD研究のバイオマーカー探索の効率を高める方法をご覧ください。

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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