FCMAB198F

Milli-Mark^® Anti-CD54-FITC Antibody, clone 6.5B5

clone 6.5B5, Milli-Mark^®, from mouse

• 別名: Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: FITC conjugate
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 6.5B5, monoclonal
• 化学種の反応性: human
• メーカー／製品名: Milli-Mark^®
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_000192
• UniProtアクセッション番号: P05362
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ICAM1(3383)

詳細

詳細

The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family. The ligand for ICAM-1 is LFA-1 (leucocyte function associated-1 protein) (Berendt, 1992). ICAM-1 is widely expressed on many cell types, although the degree of expression by unstimulated resting cells varies. As a cellular activation antigen the expression of ICAM-1 is up-regulated upon cell activation, being induced particularly in response to cytokines such as interleukin-1, tumor necrosis factor, and interferon- (Berendt, 1992; Wellicome, 1990; Thornhill, 1990). ICAM-1 might be a receptor for rhinovirus (Staunton, 1989). In rejecting kidneys the antibody stains all infiltrating cells strongly as well as glomerulus epithelium, endothelium on capillaries, large vessels, and mesangium (Waugh, 1989).

特異性

Antibody recognizes Human CD54 antigen.

免疫原

TNF-activated human umbilical vein endothelial cells

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
免疫グロブリン及び免疫

Milli-Mark Anti-CD54-FITC Antibody, clone 6.5B5 is an antibody against CD54 for use in FC.

品質

Evaluated by flow cytometry using human lymphocytes

ターゲットの説明

90 kDa (Springer, 1990)

物理的形状

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

保管および安定性

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

アナリシスノート

Control
Human Lymphocytes

法的情報

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable