ABN466

Anti-NANOS2 Antibody

from rabbit, purified by affinity chromatography

• 別名: Nanos homolog 2, NOS-2, NANOS2
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: rat, human
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: P60321
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... NANOS2(339345)

詳細

詳細

Nanos homolog 2 (NANOS2) is a zinc-finger containing, RNA-binding protein belonging to the nanos family. NANOS2 plays an important role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. It has been implicated in germ cell development in both invertebrates and vertebrates. Unlike NANOS1, whose expression in mice is dispensable, the NANOS2 and NANOS3 proteins are required for germ cell development. NANOS2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while NANOS3-null PGCs are lost during the migration stage regardless of sex.

特異性

This antibody recognizes the N-terminus of NANOS2.

免疫原

KLH-conjugated linear peptide corresponding to the N-terminus of human NANOS2.

アプリケーション

Detect Nanos homolog 2 using this rabbit polyclonal antibody, Anti-NANOS2 Antibody validated for use in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected NANOS2 in human brain tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected NANOS2 in human testis cells.

品質

Evaluated by Western Blotting in rat brain tissue.

Western Blotting Analysis: 2 µg/mL of this antibody detected NANOS2 in 15 µg of rat brain tissue.

ターゲットの説明

~15 kDa observed

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable