AB2994

Anti-Phospho-Bid (Ser65) Antibody

from rabbit, purified by affinity chromatography

• 別名: BH3-interacting domain death agonist, p22 BID, BID
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• テクニック: western blot: suitable
• NCBIアクセッション番号: NM_001196.2
• UniProtアクセッション番号: P55957-2
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pSer65)
• 遺伝子情報: human ... BID(637)

詳細

詳細

Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. Bid induces ICE-like proteases and apoptosis. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the major proteolytic product p15 Bid translocates to mitochondria where it triggers cytochrome c release.

特異性

Other species have not been tested.

The antibody reacts with the 22 kDa phospho-Bid-S65 protein.

免疫原

Epitope: Ser65

アプリケーション

Research Category
アポトーシス及び癌

Research Sub Category
アポトーシス-追加

Anti-Phospho-Bid (Ser65) Antibody detects level of Phospho-Bid (Ser65) & has been published & validated for use in WB.

品質

Evaluated by Western Blot on Jurkat cell lysate treated with (+/-) insulin.

Western Blot Analysis:
A 1:100~500 dilution of this antibody detected phospho-Bid-S65 on jurkat cell lysate treated with (+/-) insulin.

ターゲットの説明

22 kDa

物理的形状

Antigen Affinity Purified

Purified in PBS with 0.09% NaN3.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Western Blot:: Jurkat cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable