AB15322

Anti-Nicotinic Acetylcholine Receptor α4 Antibody

from rabbit, purified by affinity chromatography

• 別名: Cholinergic receptor, nicotinic, alpha 4 (neuronal), Cholinergic receptor, nicotinic, alpha polypeptide 4, Neuronal nicotinic acetylcholine receptor alpha-4 subunit, Neuronal acetylcholine receptor subunit alpha-4
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human, rat, mouse
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_077330
• UniProtアクセッション番号: P09483
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CHRNA4(1137)

詳細

詳細

Nicotinic acetylcholine receptors, or nAChRs, are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons. nAChR is triggered by the binding of the neurotransmitter acetylcholine (ACh) and is also opened by nicotine. After binding ACh, the nAChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. nAChRs are present in many tissues in the body: the neuronal receptors are present in the central nervous system and the peripheral nervous system; and the neuromuscular receptors are found in the neuromuscular junctions of somatic muscles. Neuronal AChR is composed of two different types of subunits: alpha (α) and beta (β).

特異性

This antibody recognizes Nicotinic Acetylcholine Receptor α4.

免疫原

Epitope: Extracellular Domain

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from residues of Nicotinic Acetylcholine Receptor α4.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
神経伝達物質及び受容体

Detect Nicotinic Acetylcholine Receptor α4 using this Anti-Nicotinic Acetylcholine Receptor α4 Antibody validated for use in WB.

品質

Evaluated by Western Blot in rat e16 brain lysate.
Western Blot Analysis: : 1:1,000 dilution of this lot detected Nicotinic Acetylcholine Receptor α4 in 10 µg of e16 rat brain lysate.

ターゲットの説明

Approx. 55 kDa

物理的形状

Antigen Affinity Purified

Rabbit purified polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Maintain refrigerated at 2-8°C for up to 12 months from date of receipt.

アナリシスノート

Control
Rat e16 brain lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable