AB15242

Anti-zDHHC8 Antibody

from rabbit, purified by affinity chromatography

• 別名: Zinc finger DHHC domain-containing protein 8, Zinc finger protein 378, membrane-associated DHHC8 zinc finger protein, zinc finger, DHHC domain containing 8, zinc finger, DHHC domain like containing 1, zinc finger, DHHC-type containing 8
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• クローン: polyclonal
• application: WB
• 化学種の反応性: rat, human
• テクニック: western blot: suitable
• citations: 1

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: rat, human
• 化学種の反応性（ホモロジーによる予測）: horse, bovine, Xenopus, chicken, pig, chimpanzee, ape, opossum, mouse, dog
• テクニック: western blot: suitable
• UniProtアクセッション番号: Q9ULC8
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: chimpanzee ... Zdhhc8(458662) ; human ... ZDHHC8(29801)

詳細

詳細

Six genes in the 1.5 Mb region of chromosome 22 deleted in DiGeorge/22q11 deletion syndrome–Mrpl40, Prodh, Slc25a1, Txnrd2, T10, and Zdhhc8–encode mitochondrial proteins. All six genes are expressed in the
brain, and maximal expression coincides with peak forebrain synaptogenesis shortly after birth. Furthermore, their protein products are associated with brain mitochondria, including those in synaptic terminals. Among the six, only Zddhc8 influences mitochondria-regulated apoptosis when overexpressed, and appears to interact biochemically with established mitochondrial proteins. Zdhhc8 has an apparent interaction with Uqcrc1, a component of mitochondrial complex III. The two proteins are coincidently expressed in pre-synaptic processes; however, Zdhhc8 is more frequently seen in glutamatergic terminals (1).

特異性

Cat. AB15242 recognizes the C-terminus of zDHHC8.

免疫原

Epitope: C-Terminus

Syntheic linear peptide.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
ニューロン発生

Anti-zDHHC8 Antibody is an antibody against zDHHC8 for use in WB.

品質

Routinely evaluated by western blot in fetal human brain lysate.

ターゲットの説明

~71 kDa

物理的形状

ImmunoAffinity Purified

Purified in PBS with 0.05% NaN3

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution.

アナリシスノート

Control
Fetal human brain

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable