8.56057

H-Pro-2-ClTrt resin

Novabiochem^®

• 別名: Chlorotrityl Resin
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• 品質水準: 400
• 製品種目: Novabiochem^®
• 形状: beads
• 反応適合性: reaction type: Fmoc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 保管温度: 2-8°C

詳細

詳細

Pre-loaded resin for synthesis of protected peptide acids containing a C-terminal proline amino-acid residue by Fmoc SPPS. Cleavage of the protected peptide is effected by treatment with 1% TFA in DCM or 20% TFE in DCM. The use of this resin enables the synthesis of peptides containing C-terminal Pro without risk of diketopiperazine formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

アプリケーション

• B Yakimova et al. Reported the use of H-Pro-2-ClTrt resin in the synthesis of short peptides with potential ACE inhibitory activity (B Yakimova, et al., 2021).
• S Wang et al. Detailed the use of H-Pro-2-ClTrt resin in a study on aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase (S Wang, et al., 2022).
• LP Vu et al. Described the use of H-Pro-2-ClTrt resin in the synthesis of inhibitors for serine proteases (LP Vu, et al., 2022).

関連事項

Replaces: 04-12-2805

アナリシスノート

Color (visual): pale yellow to beige
Appearance of substance (visual): beads
Identity (of the substitution): passes test
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 1.10 mmol/g
Swelling Volume (in DMF): lot specific value
The polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable