8.53022

Boc-Trp(For)-OH

Novabiochem^®

• 別名: Boc-Trp(For)-OH, N-α-t.-Boc-N-in-formyl-L-tryptophan
• 実験式（ヒル表記法）: C₁₇H₂₀N₂O₅
• CAS番号: 47355-10-2
• 分子量: 332.35
• MDL番号: MFCD00065992
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• 品質水準: 200
• 製品種目: Novabiochem^®
• アッセイ: ≥98% (TLC)
• フォーム: powder
• 反応適合性: reaction type: Boc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• mp: 100 °C (decomposition)
• アプリケーション: peptide synthesis
• 保管温度: 15-25°C
• SMILES記法: [n]1(c2c(c(c1)C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cccc2)C=O
• InChI: 1S/C17H20N2O5/c1-17(2,3)24-16(23)18-13(15(21)22)8-11-9-19(10-20)14-7-5-4-6-12(11)14/h4-7,9-10,13H,8H2,1-3H3,(H,18,23)(H,21,22)/t13-/m0/s1
• InChI Key: IHXHBYFWSOYYTR-ZDUSSCGKSA-N

詳細

詳細

Standard building block for introduction of tryptophan by Boc SPPS. The formyl group is stable to standard high HF cleavage but can be removed by HF containing thiophenol ^[1,2,3]. The formyl group can also be removed with piperidine in DMF prior to HF cleavage.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

^[1] M. Ohno, et al. (1973) Bull. Chem. Soc. Jpn., 46, 3280.
^[2] W. F. Heath, et al. (1982) J. Chem. Soc., Chem. Commun., 896.
^[3] G. R. Matsueda (1982) Int. J. Peptide Protein Res., 20, 26.

関連事項

Replaces: 04-12-0087

アナリシスノート

Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(0811)): ≥ 98 %
Purity (TLC(011A)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable