676950-M

Veratridine

A Na⁺ channel opener.

• 別名: Veratridine
• 実験式（ヒル表記法）: C₃₆H₅₁NO₁₁
• CAS番号: 71-62-5
• 分子量: 673.79
• MDL番号: MFCD00082515
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• アッセイ: ≥98% (TLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white to yellow
• 溶解性: DMSO: 25 mg/mL; ethanol: 25 mg/mL
• 保管温度: 2-8°C
• InChI: 1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29(39)20-7-8-21(45-4)22(14-20)46-5/h7-8,14,19,23-28,38,40-44H,6,9-13,15-18H2,1-5H3/t19-,23-,24-,25-,26-,27-,28-,30-,31+,32+,33+,34+,35-,36-/m0/s1
• InChI Key: FVECELJHCSPHKY-YFUMOZOISA-N

詳細

詳細

A Na⁺ channel opener. Increases intracellular Ca²⁺ levels without affecting Na⁺ - Ca²⁺ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na⁺ channels causing persistent activation. Induces cell death in bovine chromaffin cells.

A Na⁺ channel opener. Increases intracellular Ca²⁺ levels without affecting Na⁺-Ca²⁺ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na⁺ channels causing persistent activation. Induces cell death in bovine chromaffin cells.

生物化学的／生理学的作用

Primary Target
Na+ channel

警告

Toxicity: Highly Toxic (H)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Maroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
Rando, T.A., et al. 1989. J. Gen. Physiol.93, 43.
Rando, T.A., et al. 1986. Mol. Pharmacol.29, 467.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H300 + H310 + H330 - H315 - H319 - H335
• 注意書き: P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable