648471

Trolox

A cell-permeable, water-soluble derivative of vitamin E with antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.

• 別名: Trolox, 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
• 実験式（ヒル表記法）: C₁₄H₁₈O₄
• CAS番号: 53188-07-1
• 分子量: 250.29
• MDL番号: MFCD00006846
• UNSPSCコード: 12352205

特性

• 詳細: RTECS - DJ2273000
• アッセイ: ≥98% (titration)
• フォーム: powder
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white to off-white; white to pale green; white to pale yellow
• 溶解性: water: 0.5 mg/mL (slightly soluble); ethanol: 150 mg/mL; methanol: soluble
• 輸送温度: ambient
• 保管温度: 2-8°C
• SMILES記法: O1C(CCc2c1c(c(c(c2C)O)C)C)(C)C(=O)O
• InChI: 1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
• InChI Key: GLEVLJDDWXEYCO-UHFFFAOYSA-N

詳細

詳細

A cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.

アプリケーション

• Structural characterization of peroxyl radical oxidative products of antioxidant peptides from hydrolyzed proteins.: This study highlights the application of Trolox in understanding the oxidative modifications of antioxidant peptides, which could help in the development of more effective antioxidative therapies and supplements (Esfandi et al., 2024).


• Extraction of bioactive compounds from pecan nutshell: An added-value and low-cost alternative for an industrial waste.: Trolox is utilized to evaluate the antioxidant capacity of bioactive extracts from pecan shells, presenting a sustainable approach to utilizing agricultural waste (Cardona Jimenez et al., 2024).


• Investigation into the role of carboxylic acid and phenolic hydroxyl groups in the plant biostimulant activity of a humic acid purified from an oxidized sub-bituminous coal.: Utilizing Trolox equivalent antioxidant capacity (TEAC) assay, this research explores the bio-stimulatory properties of humic substances, enhancing our understanding of their role in agriculture (Lamar et al., 2024).

警告

Toxicity: Harmful (C)

再構成

Following reconstitution, aliquot and freeze (-20°C). Ethanol stock solutions are stable for up to 1 month at -20°C.

その他情報

Salgo, M.G. and Pryor, W.A. 1996. Arch. Biochem. Biophys. 333, 482.
McClain, D.E., et al. 1995. FASEB J. 9, 1345.
Salgo, M.G., et al. 1995. Arch. Biochem. Biophys.322, 500.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable