5.00111

Cocarboxylase tetrahydrate

(thiamine pyrophosphate tetrahydrate), EMPROVE^® API

• 別名: Cocarboxylase tetrahydrate
• 実験式（ヒル表記法）: C₁₂H₁₈N₄O₇P₂S · 4H₂O
• CAS番号: 68684-55-9
• 分子量: 496.37
• UNSPSCコード: 12352107
• EC Index Number: 205-230-7

特性

• 品質水準: 600
• 製品種目: EMPROVE^® API
• 形状: solid
• pH: 2.4-3.2 (20 °C, 100 g/L in H₂O)
• 溶解性: 55 g/L
• かさ密度: 450 kg/m³
• アプリケーション: liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• 保管温度: 2-25°C
• InChI: 1S/C12H18N4O7P2S.4H2O/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;;;;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);4*1H2
• InChI Key: KLOLNRGPRQYTIW-UHFFFAOYSA-N

詳細

詳細

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Cocarboxylase tetrahydrate Emprove^® API is a source for Vitamin B1 for use in clinical nutrition, vitamin supplements and infusion for Vitamin B1 deficiency. Cocarboxylase Tetrahydrate (thiamine diphosphoric acid ester tetrahydrate) Emprove^® API is manufactured according to ICH Q7 guidelines. An ASMF is available.

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

The substance 5.00111 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable