487955

NOC-12

A nitric oxide (NO) donor similar to NOC-5 and NOC-7 but with a much longer half-life of NO release.

• 別名: NOC-12, N-Ethyl-2-(1-ethyl-2-hydroxy-2-nitrosohydrazino)ethanamine
• 実験式（ヒル表記法）: C₆H₁₆N₄O₂
• CAS番号: 146724-89-2
• 分子量: 176.22
• MDL番号: MFCD00674898
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• アッセイ: ≥90% (HPLC)
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic); protect from light
• 色: white
• 溶解性: 0.1 M NaOH: soluble; water: soluble
• 輸送温度: ambient
• 保管温度: −20°C
• InChI: 1S/C6H16N4O2/c1-3-7-5-6-9(4-2)10(12)8-11/h7,11H,3-6H2,1-2H3/b10-8-
• InChI Key: DPKCLDSTXVCYSN-NTMALXAHSA-N

詳細

詳細

A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) and NOC-7 (Cat. No. 487952) but with a much longer half-life of NO release. Half-life (t_½) in PBS, pH 7.4 is 327 minutes at 22°C. Inhibits the proliferation of arterial smooth muscle cells in a dose-dependent manner. Relatively stable in alkaline solution (pH ≥10.0).

生物化学的／生理学的作用

Cell permeable: no

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

その他情報

Ambalavanan, N., et al. 1999. Biol. Neonate76, 291.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02
• シグナルワード: Danger
• 危険有害性情報: H242
• 注意書き: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危険有害性の分類: Self-react. C
• 保管分類コード: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable