444241

MMP-2/MMP-9 Inhibitor I

The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 別名: MMP-2/MMP-9 Inhibitor I, (2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
• 実験式（ヒル表記法）: C₂₁H₁₉NO₄S
• CAS番号: 193807-58-8
• 分子量: 381.44
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: DMSO: 200 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

A potent inhibitor of MMP-2 (IC₅₀ = 310 nM) and MMP-9 (IC₅₀ = 240 nM). Orally active in animal models of tumor growth and metastasis.

A potent inhibitor of MMP-2 (gelatinase A; IC₅₀ = 310 nM) and MMP-9 (gelatinase B; IC₅₀ = 240 nM).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
MMP-2, MMP-9

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 310 nM and 240 nM against MMP-2 and MMP-9

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

その他情報

Tamura, Y., et al. 1998. J. Med. Chem.41, 640.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable